Pantothenate kinase-associated neurodegeneration
MONDO:0009319Pantothenate kinase-associated neurodegeneration (PKAN) is the most common type of neurodegeneration with brain iron accumulation (NBIA), a rare neurodegenerative disorder characterized by progressive extrapyramidal dysfunction (dystonia, rigidity, choreoathetosis), iron accumulation on the brain and axonal spheroids in the central nervous system.
Also known as: brain iron accumulation type I syndrome, Hallervorden-Spatz disease, Hallervorden-Spatz syndrome, NBIA1, PKAN, neurodegeneration with brain iron accumulation 1, neurodegeneration with brain iron accumulation type 1, pantothenate kinase-associated neurodegeneration
17 clinical trials for this condition and its sub-types, 4 tagged with Pantothenate kinase-associated neurodegeneration itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pantothenate kinase-associated neurodegeneration
-
AI hunts for early clues to Parkinson's and Alzheimer's progression
Knowledge-focused Recruiting nowThis study follows 600 people with neurodegenerative diseases such as Parkinson's, Alzheimer's, and related conditions over 1 to 10 years. Researchers collect data from routine clinical exams, brain imaging, movement analysis, and blood tests. They use statistical tools and artif…
Sponsor: Casa di Cura San Raffaele Cassino • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
-
Major study tracks rare brain diseases to unlock their secrets
Knowledge-focused Recruiting nowThis study follows 1500 people with rare genetic brain disorders to learn how these diseases progress. Researchers measure thinking, movement, and daily living skills over time, and also look at brain scans and body fluids. The goal is to better understand the diseases and how tr…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC