Pancreatic intraductal papillary-mucinous neoplasm
MONDO:0004286A usually slow-growing epithelial neoplasm with ductal differentiation that arises from the exocrine pancreas and grows mostly within the pancreatic ducts. Grossly, it is characterized by the presence of intraductal masses. Morphologically, there is proliferation of mucin-producing cells within the pancreatic ducts, intraductal accumulation of mucin, and a papillary growth pattern. It may be associated with the presence of an invasive carcinoma. It usually occurs in older patients. Signs and symptoms include epigastric pain, weight loss, jaundice, chronic pancreatitis, and diabetes mellitus.
Also known as: IPMN, pancreatic IPMN, pancreatic intraductal papillary-mucinous neoplasm, pancreatic intraductal papillary-mucinous tumor, pancreatic intraductal papillary-mucinous tumour, intraductal papillary mucinous neoplasm
2909 clinical trials for this condition and its sub-types, 38 tagged with Pancreatic intraductal papillary-mucinous neoplasm itself.
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Browse by category →Sub-types of Pancreatic intraductal papillary-mucinous neoplasm
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Zapping pancreatic tumors without surgery: a safer approach?
Disease control Not yet recruitingThis early study tests if a new, needle-based treatment using brief electric pulses can safely destroy certain pancreatic tumors without surgery. The treatment aims to spare healthy tissue nearby. About 12 adults with specific pancreatic cysts or low-grade tumors will be enrolled…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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AI joins the hunt for hidden pancreatic cancer
Diagnosis Not yet recruitingResearchers are testing whether a previously validated artificial intelligence model can help identify high-grade dysplasia or pancreatic cancer in real time during a procedure called digital per-oral pancreatoscopy. The study enrolls 60 adults who need this procedure for suspect…
Sponsor: Instituto Ecuatoriano de Enfermedades Digestivas • Aim: Diagnosis
Last updated Sep 11, 2026 00:00 UTC
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Scientists hunt for biomarkers to catch pancreatic cancer before it strikes
Diagnosis Not yet recruitingThis study aims to find molecular clues that could predict whether certain pancreatic growths will turn into cancer. Researchers will analyze tissue from patients having pancreatic surgery, using advanced genetic and protein tests on both the original tissue and lab-grown 3D cell…
Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Diagnosis
Last updated Jul 18, 2026 00:00 UTC
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New ultrasound technique could eliminate need for contrast dye in pancreatic cyst exams
Diagnosis Not yet recruitingThis study investigates whether a new ultrasound technology called Superb Microvascular Imaging (SMI) can accurately analyze material inside pancreatic cysts (PIMPTs) without using a contrast agent. Currently, doctors inject a contrast dye during endoscopic ultrasound to assess c…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC
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Can pancreatic Cancer's inflammatory footprint be stopped?
Knowledge-focused Not yet recruitingThis observational study looks at how pancreatic cancer changes immune cells in the blood. Researchers will compare blood samples from 50 people with newly diagnosed, untreated pancreatic cancer to 50 age-matched people with a non-cancerous pancreatic condition. They aim to ident…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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New study aims to reduce dangerous clots after complex pancreatic surgery
Knowledge-focused Not yet recruitingThis study looks at why some patients develop blood clots after pancreatic surgery that also involves removing a piece of a major vein. Researchers will collect information from over 1,000 patients across many hospitals to see how surgical techniques and blood-thinning medication…
Sponsor: Sahlgrenska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Pancreatic cyst study seeks better way to spot danger
Knowledge-focused Not yet recruitingThis study looks at whether people with pancreatic cysts (IPMN) also have trouble digesting food due to poor pancreatic function. Researchers will follow 600 adults to see if this digestive problem is linked to cyst growth or cancer risk. The goal is to find a simple test that he…
Sponsor: A.O.U. Città della Salute e della Scienza • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC