Pancreatic carcinoma with mixed differentiation

MONDO:0044727

A rare carcinoma with a poor prognosis, characterized by the presence of a mixture of exocrine and neuroendocrine malignant epithelial cells in both the pancreas and metastatic sites. Symptoms include jaundice, abdominal pain, and weight loss.

Also known as: MiNEN of pancreas, mixed exocrine-endocrine carcinoma of the pancreas, pancreatic MiNEN, pancreatic carcinoma with mixed differentiation, pancreatic mixed neuroendocrine-nonneuroendocrine neoplasm, mixed neuroendocrine-nonneuroendocrine neoplasm of pancreas

2883 clinical trials for this condition and its sub-types, 3 tagged with Pancreatic carcinoma with mixed differentiation itself.

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Where it sits in the disease tree

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↑ Exocrine pancreatic carcinoma (1037) ↑ Digestive system mixed adenoneuroendocrine carcinoma (3)

Including sub-types (2883) Tagged with Pancreatic carcinoma with mixed differentiation (3)

Trials to join now! 2 Completed 1

Can a black seed extract boost immunotherapy against a rare cancer?

Disease control Completed

This pilot trial is testing whether adding NP-101, a compound from black seed oil, to two immunotherapy drugs (nivolumab and ipilimumab) can help control advanced or metastatic extra-pulmonary neuroendocrine carcinoma (EP-NECA) that has progressed after initial treatment. About 1…

Phase 1 • Sponsor: Amr Mohamed MD • Aim: Disease control

Last updated Aug 12, 2026 00:00 UTC

Pancreatic carcinoma with mixed differentiation

Where it sits in the disease tree

Can a black seed extract boost immunotherapy against a rare cancer?