Pancreatic cancer, susceptibility to, 4

MONDO:0013685

Any familial pancreatic carcinoma in which the cause of the disease is a mutation in the BRCA1 gene.

Also known as: BRCA1 familial pancreatic carcinoma, familial pancreatic carcinoma caused by mutation in BRCA1, pancreatic cancer, susceptibility to, 4, pancreatic cancer, susceptibility to, type 4, PNCA4, susceptibility to pancreatic cancer 4

33 clinical trials for this condition and its sub-types, 1 tagged with Pancreatic cancer, susceptibility to, 4 itself.

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Where it sits in the disease tree

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Including sub-types (33) Tagged with Pancreatic cancer, susceptibility to, 4 (1)

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New drug combo targets BRCA cancers in early trial

Disease control Ongoing

This early-phase study tests a combination of two drugs, niraparib and dostarlimab, in 18 adults with BRCA-mutated breast, pancreas, or ovary cancer that has spread or cannot be surgically removed. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the…

Phase 1 • Sponsor: University of Washington • Aim: Disease control

Last updated Aug 22, 2026 00:00 UTC

Pancreatic cancer, susceptibility to, 4

Where it sits in the disease tree

New drug combo targets BRCA cancers in early trial