Palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome
MONDO:0012530Palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome is characterized by sex reversal in males with a 46, XX (SRY-negative) karyotype, palmoplantar hyperkeratosis and a predisposition to squamous cell carcinoma. To date, five cases (four of whom were brothers) have been described. The etiology is unknown.
Also known as: palmoplantar hyperkeratosis with squamous cell carcinoma of skin and sex reversal, palmoplantar hyperkeratosis-XX sex reversal-predisposition to squamous cell carcinoma syndrome, palmoplantar hyperkeratosis and true hermaphroditism, palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,XX SEX reversal
5 clinical trials for this condition and its sub-types, 0 tagged with Palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome itself.
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