Otorhinolaryngologic disease
MONDO:0024623Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases.
Also known as: ear, nose and throat disorder, ear, nose or throat disorder, ear/nose/throat disease, otolaryngologic disorder, otorhinolaryngologic disease, ENT disease, ENT diseases, disease, ENT
1326 clinical trials for this condition and its sub-types, 15 tagged with Otorhinolaryngologic disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Otorhinolaryngologic disease
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Disorder of pharynx 3 trials · 598 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 497 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 280 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 28 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Nasal disorder 3 trials · 375 incl. sub-types
5 sub-types
- Nasal cavity disorder 3 trials · 226 incl. sub-types Sub-types →
- Paranasal sinus disorder 12 trials · 163 incl. sub-types Sub-types →
- Anosmia 35 trials Sub-types →
- Nasal cavity and paranasal sinus lethal midline granuloma 0 trials
- Nasal dermoid cyst 0 trials
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Disorder of ear 8 trials · 254 incl. sub-types
6 sub-types
- Inner ear disorder 8 trials · 149 incl. sub-types Sub-types →
- Middle ear disorder 3 trials · 75 incl. sub-types Sub-types →
- Ear infection 9 trials · 40 incl. sub-types Sub-types →
- External ear disorder 0 trials · 13 incl. sub-types Sub-types →
- Hyperacusis 10 trials Sub-types →
- Ear neoplasm 0 trials · 3 incl. sub-types Sub-types →
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Lip and oral cavity squamous cell carcinoma 21 trials · 159 incl. sub-types
1 sub-type
- Oral cavity squamous cell carcinoma 141 trials · 156 incl. sub-types Sub-types →
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Hereditary otorhinolaryngologic disease 0 trials · 102 incl. sub-types
21 sub-types
- X-linked mixed hearing loss with perilymphatic gusher 32 trials
- Benign paroxysmal positional vertigo 18 trials
- Meniere disease 16 trials Sub-types →
- Motion sickness 14 trials · 16 incl. sub-types Sub-types →
- Familial congenital nasolacrimal duct obstruction 7 trials
- Choanal atresia 4 trials Sub-types →
- Otosclerosis 4 trials Sub-types →
- Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome 2 trials
- Familial thyroglossal duct cyst 2 trials
- BNAR syndrome 1 trial
- Aural atresia, congenital 1 trial
- Second branchial cleft anomaly 1 trial
- Short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome 1 trial
- X-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome 0 trials
- Bifid nose, autosomal recessive 0 trials Sub-types →
- Familial nasal acilia 0 trials
- Isolated congenital anosmia 0 trials
- Nasal dermoid cyst 0 trials
- Tonsillar lymphoma 0 trials
- Tympanic paraganglioma 0 trials
- Vertigo, benign recurrent, 1 0 trials
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Idiopathic bilateral vestibulopathy 14 trials
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Laryngeal abductor paralysis 10 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Microtia 8 trials
1 sub-type
- Ear without helix 0 trials
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Congenital tracheomalacia 6 trials
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Autoimmune disease of ear, nose and throat 0 trials · 4 incl. sub-types
7 sub-types
- Autoimmune inner ear disease 2 trials
- Autoimmune uveitis 2 trials
- Cogan syndrome 0 trials
- IgG4-related dacryoadenitis and sialadenitis 0 trials
- IgG4-related submandibular gland disease 0 trials
- Autoimmune retinopathy 0 trials
- Eosinophilic angiocentric fibrosis 0 trials
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Cysts and fistulae of the face and oral cavity 0 trials · 3 incl. sub-types
13 sub-types
- Familial thyroglossal duct cyst 2 trials
- First branchial cleft anomaly 1 trial
- Second branchial cleft anomaly 1 trial
- Cervical dermoid cyst 0 trials
- Cervicofacial fibrochondroma 0 trials
- Commissural lip fistula 0 trials
- Digestive duplication cyst of the tongue 0 trials
- Facial dermoid cyst 0 trials Sub-types →
- Fourth branchial cleft anomaly 0 trials
- Lower lip fistula 0 trials
- Nasal dorsum fistula/cyst 0 trials
- Pinnae fistula or cyst 0 trials
- Third branchial cleft anomaly 0 trials
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Mal de Debarquement 2 trials
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Anotia 1 trial
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Bifid nose 0 trials · 1 incl. sub-types
3 sub-types
- BNAR syndrome 1 trial
- Bifid nose, autosomal dominant 0 trials
- Bifid nose, autosomal recessive 0 trials Sub-types →
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Arrhinia 0 trials
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Congenital tracheal stenosis 0 trials
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Epignathus 0 trials
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Isolated congenital syngnathia 0 trials
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Laryngeal neuroendocrine neoplasm 0 trials
1 sub-type
- Laryngeal small cell carcinoma 0 trials
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Laryngotracheal angioma 0 trials
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Larynx atresia 0 trials
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Middle ear anomaly 0 trials
3 sub-types
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Nasal encephalocele 0 trials
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Nasal ganglioglioma 0 trials
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Nasal glial heterotopia 0 trials
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Nasolacrimal duct cyst 0 trials
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Polyrrhinia 0 trials
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Proboscis lateralis 0 trials
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Silent sinus syndrome 0 trials
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Supernumerary nostril 0 trials
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Supratip dysplasia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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One-Time injection aims to restore hearing in children born deaf
Cure OngoingThis trial tests a gene therapy called SENS-501 for children aged 6 to 31 months who are severely or profoundly deaf due to mutations in the otoferlin gene. The therapy is injected directly into one inner ear to deliver a working copy of the gene. The goal is to restore natural h…
Phase 1/2 • Sponsor: Sensorion • Aim: Cure
Last updated Jul 10, 2026 00:00 UTC
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One shot to restore hearing? new drug takes on steroids
Disease control OngoingThis study tests a single injection of a new drug called AC102 into the ear, comparing it to standard steroid pills for sudden hearing loss. About 210 adults with hearing loss in one ear will take part. The goal is to see if the injection improves hearing better than steroids, wi…
Phase 2 • Sponsor: AudioCure Pharma GmbH • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Could a tiny jolt to the head diagnose balance problems?
Diagnosis By invitation onlyThis early study will test whether weak electrical currents applied to the head can help diagnose balance disorders like vestibular schwannoma and vestibular neuritis. Researchers will measure how 30 people with these conditions sway or move in response to the stimulation. The go…
Sponsor: Aalto University • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC
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Robotic surgery or radiation? new study compares which is better for throat cancer patients' quality of life
Symptom relief OngoingThis study compares two treatments for early-stage throat cancer: robotic surgery (TORS) or radiation therapy (IMRT). It looks at which one leads to better swallowing function and overall quality of life. About 138 adults with HPV-related throat cancer are taking part. The goal i…
Sponsor: Christian von Buchwald • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New monitor may predict heart danger during nose surgery
Knowledge-focused OngoingThis study tests whether a device called the Analgesia Nociception Index (ANI) can predict and prevent a sudden drop in heart rate (trigeminal cardiac reflex) during nasal septoplasty. 90 adults undergoing nose surgery will be monitored either with standard tools or with the ANI …
Sponsor: Fayoum University Hospital • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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French study tracks Dupilumab's Real-World impact on severe nasal polyps
Knowledge-focused OngoingThis study follows 150 adults in France with severe chronic rhinosinusitis and nasal polyps who are already taking dupilumab (Dupixent®). Researchers will collect data on patient characteristics, disease history, and treatment patterns over two years. The goal is to see how the d…
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC