Osteoradionecrosis
MONDO:0043735Necrosis of bone following radiation injury.
Also known as: osteoradionecrosis, Osteoradionecroses, radiation necrosis of bone
15 clinical trials for this condition and its sub-types, 14 tagged with Osteoradionecrosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Osteoradionecrosis
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Osteoradionecrosis of the mandible 5 trials
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New combo therapy aims to heal Radiation-Damaged jaw bone
Disease control Recruiting nowRadiation for head and neck cancer can sometimes cause a serious side effect: dead bone in the jaw (osteoradionecrosis). This pilot study tests whether adding a drug cocktail called PENTOCLO to standard hyperbaric oxygen therapy helps more than oxygen alone. Twenty-four adults wi…
Phase 3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Jun 26, 2026 15:36 UTC
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5-Minute MRI could solve brain tumor mystery after radiation
Diagnosis Recruiting nowThis study is testing a new, quick MRI technique called Magnetic Resonance Fingerprinting (MRF) to better tell the difference between a brain tumor coming back and damage from radiation therapy (radiation necrosis). About 90 people will take part, including healthy volunteers, pa…
Sponsor: Case Comprehensive Cancer Center • Aim: Diagnosis
Last updated Sep 17, 2026 00:00 UTC
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New MRI scan could predict jaw bone damage in cancer patients
Diagnosis Recruiting nowThis study is testing whether a special type of MRI (called DCE-MRI) can predict jaw bone damage (osteoradionecrosis) in head and neck cancer patients who have had radiation therapy. Researchers will scan up to 1,400 participants before, during, and after radiation to see if chan…
Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:08 UTC
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Can MRI predict radiation side effects before they happen?
Knowledge-focused Recruiting nowThis study uses repeated MRI scans after radiation therapy to see if they can predict normal tissue damage, like bone death (osteoradionecrosis), in patients with oral cavity or skull base tumors. Researchers will track changes in imaging over time and link them to radiation dose…
Phase 4 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC