Osteogenesis imperfecta type 1

MONDO:0008146

Osteogenesis imperfecta type I is a mild type of osteogenesis imperfecta (OI), a genetic disorder characterized by increased bone fragility, low bone mass and susceptibility to bone fractures.

Also known as: Adair-Dighton syndrome, COL1A1-related osteogenesis imperfecta, OI type 1, OI1, Van der Hoeve syndrome, mild osteogenesis imperfecta, non-deforming osteogenesis imperfecta, osteogenesis imperfecta type 1

8 clinical trials for this condition and its sub-types, 8 tagged with Osteogenesis imperfecta type 1 itself.

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Where it sits in the disease tree

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Part of

↑ Osteogenesis imperfecta and a reduction of bone mineral density. (308)

Sub-types of Osteogenesis imperfecta type 1

Osteogenesis imperfecta with opalescent teeth, blue sclerae and wormian bones but without fractures 0 trials

Including sub-types (8) Tagged with Osteogenesis imperfecta type 1 (8)

Trials to join now! 4 Not yet finished but already full! 3 Completed 1

Blood clues may unlock mystery of brittle bone disease severity

Knowledge-focused Completed

This study looked at 66 adults with Osteogenesis Imperfecta (brittle bone disease) to see if small molecules called microRNAs in the blood are linked to how severe the condition is. Researchers compared people with mild (type 1) and severe (type 3) forms, plus healthy controls. T…

Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused

Last updated Jun 26, 2026 13:34 UTC

Osteogenesis imperfecta type 1

Where it sits in the disease tree

Blood clues may unlock mystery of brittle bone disease severity