Opioid-induced constipation
MONDO:0100187A constipation disorder caused by use of opioids. OIC may present immediately when a patient takes the opioid, or it may present gradually during opioid therapy.
Also known as: OIC
15 clinical trials for this condition and its sub-types, 13 tagged with Opioid-induced constipation itself.
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Can a drug prevent gut problems and pneumonia in Brain-Injured patients?
Disease control PausedThis study tests whether naloxegol, a drug that blocks opioid effects in the gut, can prevent constipation and pneumonia in brain-injured patients in the ICU. These patients often receive opioids for sedation, which can slow digestion and lead to serious complications. The trial …
Phase 3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Constipation study for back surgery patients withdrawn before starting
Symptom relief CancelledThis study was designed to see if the drug RELISTOR could help relieve constipation caused by opioid painkillers in people who had spinal fusion surgery. It planned to compare RELISTOR to standard laxatives in 40 patients. However, the study was withdrawn before enrolling anyone,…
Sponsor: Methodist Health System • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC