Ocular adnexal lymphoma
MONDO:0020646A non-Hodgkin lymphoma arising from the conjunctiva, lacrimal gland, lacrimal drainage apparatus, eyelids, or other orbital tissues around the eye. The vast majority of cases are extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue, however, other histologic types of lymphomas can originate from ocular adnexal tissues, including rare cases of NK/T-cell lymphomas of nasal type.
Also known as: OAL, non-Hodgkin lymphoma of ocular adnexa, ocular adnexa non-Hodgkin lymphoma, ocular adnexal lymphoma
1925 clinical trials for this condition and its sub-types, 4 tagged with Ocular adnexal lymphoma itself.
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Tiny radiation dose may tame eye lymphoma
Disease control OngoingThis study tests whether a very low dose of radiation (4 Gy) can control slow-growing B-cell lymphoma in the eye socket. About 50 adults with stage I-IV indolent lymphoma or mantle cell lymphoma will receive this targeted treatment. The goal is to shrink or stop the cancer while …
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New hope for eye cancer: targeted drug combo shows promise in early trial
Disease control OngoingThis phase II trial tests a targeted cancer drug called orelabrutinib combined with either low-dose radiation or another drug (rituximab) in 39 people with a rare eye lymphoma (ocular adnexal MALT lymphoma). The goal is to see how well the combination shrinks tumors and how safe …
Phase 2 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC