Obesity-hypoventilation syndrome

MONDO:0009763

Hypoventilation syndrome in very obese persons with excessive adipose tissue around the abdomen and diaphragm is characterized by diminished to absent ventilatory chemoresponsiveness; chronic hypoxia; hypercapnia; polycythemia; and long periods of sleep during day and night (hypersomnolence). It is a condition often related to obstructive sleep apnea but can occur separately.

Also known as: obesity-hypoventilation syndrome, Pickwickian syndrome

9 clinical trials for this condition and its sub-types, 9 tagged with Obesity-hypoventilation syndrome itself.

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Where it sits in the disease tree

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↑ Hereditary disease (18235)

Including sub-types (9) Tagged with Obesity-hypoventilation syndrome (9)

Trials to join now! 1 Not yet recruiting 2 Completed 4 Terminated 2

Smart oxygen device aims to keep COPD and surgery patients breathing easier

Symptom relief Recruiting now

This study tests a device called FreeO2 that automatically adjusts oxygen levels during noninvasive breathing support. It includes 10 patients with COPD flare-ups or after weight-loss surgery. The goal is to see if the device keeps oxygen in a safe range better than manual adjust…

Sponsor: François Lellouche • Aim: Symptom relief

Last updated Jun 26, 2026 14:13 UTC

Obesity-hypoventilation syndrome

Where it sits in the disease tree

Smart oxygen device aims to keep COPD and surgery patients breathing easier