Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

Log in / Sign up

Obesity due to leptin receptor gene deficiency

MONDO:0013992

Also known as: LEPR Deficiency, obesity due to leptin receptor gene deficiency, obesity, morbid, due to leptin receptor deficiency, leptin receptor deficiency, obesity, morbid, nonsyndromic 2

81 clinical trials for this condition and its sub-types, 1 tagged with Obesity due to leptin receptor gene deficiency itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Congenital hypogonadotropic hypogonadism (83) ↑ Inherited obesity (9)

Including sub-types (81) Tagged with Obesity due to leptin receptor gene deficiency (1)

Gene-Targeted obesity drug shows promise in phase 3 trial

Disease control Completed

This phase 3 trial is testing a drug called setmelanotide in people with obesity linked to certain gene variants (POMC, PCSK1, LEPR, NCOA1, or SH2B1). About 296 participants, aged 6 to 65, will receive either the drug or a placebo to see if it helps reduce body weight. The study …

Phase 3 • Sponsor: Rhythm Pharmaceuticals, Inc. • Aim: Disease control

Last updated Aug 08, 2026 00:03 UTC