Non-cutaneous melanoma
MONDO:0006320Melanoma is a malignant tumor of melanocytes, cells that are derived from the neural crest. Although most melanomas arise in the skin, they also may arise from mucosal surfaces or at other sites to which neural crest cells migrate. (PDQ)
Also known as: extracutaneous melanoma, non-cutaneous melanoma
1487 clinical trials for this condition and its sub-types, 6 tagged with Non-cutaneous melanoma itself.
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Sub-types of Non-cutaneous melanoma
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Mucosal melanoma 47 trials
2 sub-types
- Cervix melanoma 1 trial
- Vaginal melanoma 1 trial
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Vulvar melanoma 3 trials
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Primary melanoma of the central nervous system 2 trials · 3 incl. sub-types
3 sub-types
- Leptomeningeal melanoma 1 trial Sub-types →
- Meningeal melanomatosis 0 trials
- Spinal cord melanoma 0 trials
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Digestive system melanoma 0 trials · 2 incl. sub-types
3 sub-types
- Rectum malignant melanoma 1 trial · 2 incl. sub-types Sub-types →
- Esophageal melanoma 1 trial
- Gallbladder melanoma 1 trial
Most studied deeper sub-types
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Can a newer immunotherapy drug keep melanoma from coming back?
Disease control OngoingThis phase III trial compares the drug pembrolizumab (MK-3475) to the current standard treatments—high-dose interferon or ipilimumab—in 1,301 patients with high-risk melanoma that has been surgically removed. The goal is to see if pembrolizumab is better at preventing the cancer …
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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New drug duo takes on tough cancers: hope for advanced bladder, kidney, and melanoma patients
Disease control OngoingThis study is testing a new combination of two immunotherapy drugs (BGB-A445 and tislelizumab) in about 113 people with advanced bladder, kidney, or skin cancer that has spread. The goal is to see if the combo can shrink tumors and how safe it is. Participants must have already t…
Phase 1/2 • Sponsor: BeiGene • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Melanoma vaccine study pulled before starting
Disease control CancelledThis study aimed to test a special vaccine made from modified melanoma cells to help the immune system fight remaining cancer in people with high-risk or low-burden melanoma. It was designed for patients with certain genetic markers and stages of melanoma. However, the study was …
Phase 2/3 • Sponsor: Hadassah Medical Organization • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC