Nodular lymphocyte predominant Hodgkin lymphoma
MONDO:0044778A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)
Also known as: Hodgkin lymphoma nodular LP, NOS, Hodgkin lymphoma nodular lymphocyte predominant type, NOS, NLPHL, nodular lymphocyte predominant Hodgkin lymphoma, nodular lymphocyte predominant Hodgkin's lymphoma, nodular lymphocyte-predominant Hodgkin lymphoma
1904 clinical trials for this condition and its sub-types, 5 tagged with Nodular lymphocyte predominant Hodgkin lymphoma itself.
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Sub-types of Nodular lymphocyte predominant Hodgkin lymphoma
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New combo therapy aims to extend remission in elderly lymphoma patients
Disease control OngoingThis study is for people aged 75 or older who have been newly diagnosed with certain aggressive types of B-cell lymphoma. It tests whether adding an oral medication (CC-486, or oral azacitidine) to the standard reduced-dose chemotherapy regimen (R-miniCHOP) can help keep the canc…
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Blood test may replace scans for lymphoma monitoring
Knowledge-focused OngoingThis study is testing whether a blood test that looks for tumor DNA (called ctDNA) can predict if lymphoma will come back after first treatment. Researchers will compare this 'liquid biopsy' to standard PET scans in 108 adults with B-cell or Hodgkin lymphoma. The goal is to see i…
Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC