Newborn respiratory distress syndrome
MONDO:0700081A condition beginning in the first day of life that results from inadequate surfactant production, causing increased work of breathing and impaired gas exchange.
Also known as: RDS, respiratory distress syndrome, RDS Of newborns, RDS, respiratory distress syndrome Of newborns, hyaline membrane disease, infant ARDS, infant acute respiratory distress syndrome, infant respiratory distress syndrome
205 clinical trials for this condition and its sub-types, 49 tagged with Newborn respiratory distress syndrome itself.
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Sub-types of Newborn respiratory distress syndrome
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Can a simple color change improve breathing support for preemies?
Disease control Not yet recruitingThis trial tests whether using a colorimetric carbon dioxide (CO₂) detector to guide non-invasive breathing support (ventilation) improves care for premature infants born before 32 weeks. The detector changes color to show how well the baby is exhaling CO₂, which may help doctors…
Sponsor: Leiden University Medical Center • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Could a muscle relaxant make newborn intubation safer?
Symptom relief Not yet recruitingThis study tests whether adding a muscle relaxant (rocuronium) to standard painkiller (fentanyl) helps doctors place breathing tubes in newborns on the first try, without causing dangerous drops in oxygen or heart rate. About 102 premature or sick babies in a Brazilian NICU will …
Phase 4 • Sponsor: UEA - Universidade Do Estado Do Amazonas • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Slower lung inflation may protect preterm Babies' lungs
Symptom relief Not yet recruitingThis trial studies whether a slower inflation setting (long pressure rise time) on mechanical ventilators can improve oxygen levels in extremely preterm infants compared to the standard faster setting. About 68 babies born before 28 weeks will be randomly assigned to both setting…
Sponsor: Murdoch Childrens Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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New nasal device could ease breathing for preemies
Symptom relief Not yet recruitingThis study compares a new device called ADINA to standard high-flow nasal cannula for giving oxygen to premature babies with breathing distress. About 40 babies in the NICU will take part. The goal is to see if ADINA works as well as the usual method and to check for safety issue…
Sponsor: Loma Linda University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Which score best predicts breathing trouble in newborns?
Knowledge-focused Not yet recruitingThis study compares two scoring systems—the Silverman-Andersen score and the Downes score—to see which better predicts when a newborn with breathing problems will need a breathing tube. Researchers will follow 220 preterm and term infants receiving noninvasive breathing support. …
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:01 UTC