Nevoid basal cell carcinoma syndrome

MONDO:0007187

A rare hereditary disorder due to autosomal dominant transmission with hamartosis characterized by multiple early-onset basal cell carcinoma (BCC), multiple jaw keratocysts and skeletal abnormalities.

Also known as: Gorlin syndrome, Gorlin-Goltz syndrome, NBCCS, basal cell nevus syndrome, multiple basal cell carcinomas, nevoid basal cell cancer syndrome, nevoid basal cell carcinoma syndrome, BCNS

36 clinical trials for this condition and its sub-types, 5 tagged with Nevoid basal cell carcinoma syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary neurological disease (5791) ↑ Developmental defect during embryogenesis (1060) ↑ Hereditary neoplastic syndrome (731) ↑ Autosomal dominant disease (699) ↑ Neurocutaneous syndrome (171)

Sub-types of Nevoid basal cell carcinoma syndrome

Basal cell nevus syndrome 1 0 trials
Basal cell nevus syndrome 2 0 trials

Including sub-types (36) Tagged with Nevoid basal cell carcinoma syndrome (5)

Trials to join now! 2 Not yet finished but already full! 1 Completed 1 Terminated 1

New gel could slash facial skin cancers in rare genetic condition

Disease control Completed

This Phase 3 study tests whether a gel containing patidegib can lower the number of new basal cell carcinomas (a type of skin cancer) on the face of adults with Gorlin syndrome. Participants apply the gel or a placebo to their face twice daily for a year. The study will compare h…

Phase 3 • Sponsor: Sol-Gel Technologies, Ltd. • Aim: Disease control

Last updated Sep 20, 2026 00:00 UTC

Nevoid basal cell carcinoma syndrome

Where it sits in the disease tree

New gel could slash facial skin cancers in rare genetic condition