Neutrophil actin dysfunction
MONDO:0009755Solitary or multiple, slightly raised, pigmented lesions with irregular borders, usually measuring more than 0.6cm in greatest dimension. Morphologically, there is melanocytic atypia and the differential diagnosis from melanoma may be difficult. Patients are at an increased risk for the development of melanoma.
Also known as: Atypical Nevus, Clark Nevus, Clark's Nevus, Nevus with architectural disorder, Nevus with architectural disorder and cytologic atypia of melanocytes, dysplastic Nevus, dysplastic nevi, dysplastic nevus
1440 clinical trials for this condition and its sub-types, 6 tagged with Neutrophil actin dysfunction itself.
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Broccoli compound put to the test against melanoma
Prevention Recruiting nowResearchers are testing whether sulforaphane, a substance found in broccoli and other cruciferous vegetables, can prevent melanoma in people who have multiple atypical moles and a prior history of melanoma. Participants take sulforaphane or a placebo by mouth. The trial measures …
Phase 2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Prevention
Last updated Sep 17, 2026 00:00 UTC
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New study combines skin scans and DNA to catch melanoma earlier
Knowledge-focused Recruiting nowThis study looks at 200 people with suspicious moles that are already scheduled for removal. Researchers will use a special microscope (reflectance confocal microscopy) to take detailed images of the moles and then compare those images with genetic tests from the removed tissue. …
Sponsor: University of Modena and Reggio Emilia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Urine clue may spot kidney danger in ICU patients
Knowledge-focused Recruiting nowThis study aims to find out if a urine test can predict acute kidney failure in intensive care patients. Researchers will measure certain substances in the urine that reflect how the body produces NAD+, a key molecule for cell energy. If successful, this could help doctors identi…
Sponsor: Ramsay Générale de Santé • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC