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Neuroendocrine neoplasm

MONDO:0019496

Endocrine tumors, also referred to as neuroendocrine tumors (NETs), are defined by a common phenotype which is characterized by the expression of general markers (neuron specific enolase, chromogranin, synaptophysin) and hormone secretion products. These tumors may be localized in any part of the body and are generally discovered in non-specific situations, i.e. not immediately suggestive of NETs (tests for inherited predisposition to tumors or for a clinical syndrome caused by abnormal hormone secretion).

Also known as: APUDoma, neuroendocrine neoplasm, neuroendocrine tumor, neuroendocrine tumour

2344 clinical trials for this condition and its sub-types, 181 tagged with Neuroendocrine neoplasm itself.

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Where it sits in the disease tree

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Part of

↑ Endocrine gland neoplasm (3332)

Sub-types of Neuroendocrine neoplasm

Neuroendocrine carcinoma 106 trials · 744 incl. sub-types
12 sub-types
- Small cell carcinoma 26 trials · 542 incl. sub-types Sub-types →
- Cutaneous neuroendocrine carcinoma 78 trials
- Medullary thyroid gland carcinoma 42 trials · 53 incl. sub-types Sub-types →
- Large cell neuroendocrine carcinoma 12 trials · 31 incl. sub-types Sub-types →
- Pancreatic endocrine carcinoma 12 trials Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Liver neuroendocrine carcinoma 3 trials Sub-types →
- Thymic neuroendocrine carcinoma 3 trials Sub-types →
- Goblet cell carcinoma 2 trials
- Anal canal neuroendocrine neoplasm 1 trial Sub-types →
- Combined lung carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Vulvar neuroendocrine carcinoma 0 trials Sub-types →
Lung neuroendocrine neoplasm 21 trials · 540 incl. sub-types
5 sub-types
- Small cell lung carcinoma 514 trials · 515 incl. sub-types Sub-types →
- Pulmonary large cell neuroendocrine carcinoma 20 trials Sub-types →
- Lung carcinoid tumor 2 trials
- Combined lung carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Lung mixed small cell and squamous cell carcinoma 0 trials
Digestive system neuroendocrine neoplasm 52 trials · 167 incl. sub-types
7 sub-types
- Digestive system neuroendocrine tumor, grade 1/2 66 trials · 145 incl. sub-types Sub-types →
- Pancreatic neuroendocrine neoplasm 9 trials · 85 incl. sub-types Sub-types →
- Intestinal neuroendocrine neoplasm 7 trials · 21 incl. sub-types Sub-types →
- Gastric neuroendocrine neoplasm 3 trials · 6 incl. sub-types Sub-types →
- Liver neuroendocrine carcinoma 3 trials Sub-types →
- Gallbladder neuroendocrine neoplasm 0 trials Sub-types →
- Salivary gland small cell carcinoma 0 trials
Paraganglioma 53 trials · 57 incl. sub-types
12 sub-types
- Sympathetic paraganglioma 0 trials · 16 incl. sub-types Sub-types →
- Head and neck paraganglioma 1 trial Sub-types →
- Non-secreting paraganglioma 0 trials Sub-types →
- Parasympathetic paraganglioma 0 trials Sub-types →
- Pheochromocytoma/paraganglioma syndrome 1 0 trials
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 3 0 trials
- Pheochromocytoma/paraganglioma syndrome 4 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
- Pheochromocytoma/paraganglioma syndrome 6 0 trials
- Pheochromocytoma/paraganglioma syndrome 7 0 trials
- Sporadic pheochromocytoma/secreting paraganglioma 0 trials Sub-types →
Carcinoid tumor 33 trials · 47 incl. sub-types
7 sub-types
- Intestinal neuroendocrine tumor G1 5 trials · 8 incl. sub-types Sub-types →
- Somatostatinoma 6 trials
- Pancreatic neuroendocrine tumor G1 1 trial · 5 incl. sub-types Sub-types →
- Atypical carcinoid tumor 4 trials
- Gastric neuroendocrine tumor G1 2 trials
- Lung carcinoid tumor 2 trials
- Childhood carcinoid tumor 0 trials
Prostate neuroendocrine neoplasm 20 trials · 25 incl. sub-types
1 sub-type
- Prostate small cell carcinoma 9 trials
Hereditary pheochromocytoma-paraganglioma 6 trials
9 sub-types
- MAX-related tumor predisposition 0 trials
- TMEM127-related tumor predisposition 0 trials
- Pheochromocytoma/paraganglioma syndrome 1 0 trials
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 3 0 trials
- Pheochromocytoma/paraganglioma syndrome 4 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
- Pheochromocytoma/paraganglioma syndrome 6 0 trials
- Pheochromocytoma/paraganglioma syndrome 7 0 trials
Thymic neuroendocrine tumor 3 trials · 6 incl. sub-types
1 sub-type
- Thymic neuroendocrine carcinoma 3 trials Sub-types →
Bronchial endocrine tumor 4 trials
Ovarian neuroendocrine neoplasm 0 trials · 2 incl. sub-types
2 sub-types
- Ovarian small cell carcinoma 1 trial · 2 incl. sub-types Sub-types →
- Ovarian large-cell neuroendocrine carcinoma 0 trials
Breast neuroendocrine neoplasm 0 trials
1 sub-type
- Breast large cell neuroendocrine carcinoma 0 trials
Laryngeal neuroendocrine neoplasm 0 trials
1 sub-type
- Laryngeal small cell carcinoma 0 trials
Middle ear neuroendocrine tumor 0 trials
1 sub-type
- Tympanic paraganglioma 0 trials
Uterine corpus neuroendocrine neoplasm 0 trials
2 sub-types
- High-grade neuroendocrine carcinoma of the corpus uteri 0 trials
- Low-grade neuroendocrine tumor of the corpus uteri 0 trials

Most studied deeper sub-types

Pancreatic neuroendocrine tumor (60) Familial medullary thyroid carcinoma (23) Pancreatic insulinoma (13) Urinary bladder small cell neuroendocrine carcinoma (9) Adrenal gland pheochromocytoma (5) Cervical large cell neuroendocrine carcinoma (4) Cervical small cell carcinoma (4) Enterochromaffin cell serotonin-producing pancreatic neuroendocrine tumor (4) Non-functional pancreatic neuroendocrine tumor (4) Small intestine neuroendocrine tumor, well differentiated, low or intermediate grade (4) Cecum neuroendocrine tumor G1 (3) Gastrin-producing neuroendocrine tumor (3) Ileal neuroendocrine tumor G1 (3) Rectal neuroendocrine tumor (3) Rectum neuroendocrine neoplasm (3) Small intestinal neuroendocrine tumor G1 (3) Esophageal small cell neuroendocrine carcinoma (2) Gastric neuroendocrine tumor, well differentiated, low or intermediate grade (2) Glucagonoma (2) Pancreatic gastrin-producing neuroendocrine tumor (2)

Including sub-types (2344) Tagged with Neuroendocrine neoplasm (181)

Trials to join now! 86 Not yet recruiting 13 Not yet finished but already full! 53 Completed 25 Terminated 4