Nervous system cancer
MONDO:0005872A primary or metastatic malignant neoplasm involving the nervous system.
Also known as: nervous system neoplasm, neural neoplasm, neural tumor, neural tumour, tumor of the nervous system, tumour of the nervous system, cancer of nervous system, malignant neoplasm of nervous system
4654 clinical trials for this condition and its sub-types, 17 tagged with Nervous system cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Nervous system cancer
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Central nervous system cancer 131 trials · 1,706 incl. sub-types
20 sub-types
- Malignant glioma 250 trials · 920 incl. sub-types Sub-types →
- Brain cancer 682 trials · 902 incl. sub-types Sub-types →
- Primary central nervous system lymphoma 92 trials · 103 incl. sub-types Sub-types →
- Central nervous system sarcoma 2 trials · 74 incl. sub-types Sub-types →
- Spinal cord cancer 21 trials · 57 incl. sub-types Sub-types →
- Central nervous system primitive neuroectodermal neoplasm 8 trials · 24 incl. sub-types Sub-types →
- Central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor 1 trial · 22 incl. sub-types Sub-types →
- Malignant tumor of meninges 0 trials · 14 incl. sub-types Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Central nervous system germinoma 2 trials · 4 incl. sub-types Sub-types →
- Central nervous system melanocytic neoplasm 1 trial · 4 incl. sub-types Sub-types →
- Central nervous system endodermal sinus tumor 0 trials · 1 incl. sub-types Sub-types →
- Choriocarcinoma of the central nervous system 0 trials Sub-types →
- Embryonal carcinoma of the central nervous system 0 trials Sub-types →
- Malignant carotid body paraganglioma 0 trials
- Malignant central nervous system mesenchymal, non-meningothelial neoplasm 0 trials Sub-types →
- Malignant jugulotympanic paraganglioma 0 trials
- Mixed germ cell tumor of central nervous system 0 trials Sub-types →
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
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Sensory system cancer 0 trials · 232 incl. sub-types
7 sub-types
- Ocular cancer 10 trials · 168 incl. sub-types Sub-types →
- Tongue cancer 26 trials · 35 incl. sub-types Sub-types →
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- Auditory system cancer 0 trials · 2 incl. sub-types Sub-types →
- Malignant ear neoplasm 0 trials · 2 incl. sub-types Sub-types →
- Optic tract astrocytoma 0 trials Sub-types →
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Cutaneous neuroendocrine carcinoma 78 trials
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Peripheral nervous system cancer 0 trials · 67 incl. sub-types
18 sub-types
- Malignant peripheral nerve sheath tumor 36 trials · 38 incl. sub-types Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Peripheral primitive neuroectodermal tumor 8 trials · 9 incl. sub-types Sub-types →
- Ganglioneuroma 5 trials Sub-types →
- Malignant cranial nerve neoplasm 0 trials · 4 incl. sub-types Sub-types →
- Granular cell cancer 1 trial · 2 incl. sub-types Sub-types →
- Malignant perineurioma 1 trial
- Adrenal gland ganglioneuroblastoma 0 trials
- Cauda equina cancer 0 trials
- Isolated melanotic schwannoma 0 trials
- Malignant carotid body paraganglioma 0 trials
- Malignant jugulotympanic paraganglioma 0 trials
- Malignant mediastinal neural neoplasm 0 trials
- Mediastinum neuroblastoma 0 trials Sub-types →
- Neurofibroma of gallbladder 0 trials
- Neurofibroma of the heart 0 trials
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
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Ectomesenchymoma 1 trial
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Adrenal gland neuroblastoma 0 trials
1 sub-type
- Adrenal gland ganglioneuroblastoma 0 trials
Most studied deeper sub-types
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Can doctors watch brain metastases instead of zapping them?
Disease control Recruiting nowResearchers at the University of California, Irvine are testing whether patients with brain metastases can safely skip immediate surgery or radiation and instead have their tumors monitored with regular imaging, cognitive tests, and quality-of-life questionnaires. All participant…
Sponsor: University of California, Irvine • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Radioactive nanoparticles aimed at cancer that spreads to the Brain's lining
Disease control Recruiting nowResearchers are testing a radioactive drug called rhenium-186 obisbemeda in adults whose solid-tumor cancer has spread to the leptomeninges, the tissues lining the brain and spinal cord. The drug is a nanoliposome carrying rhenium-186, a radioactive isotope, and it is given throu…
Phase 1/2 • Sponsor: Cerenome • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Killer virus turned against childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether a specially engineered herpes virus (G207) is safe to inject directly into the brain tumors of children whose cancer has returned. Up to 24 children aged 3 to 21 will receive the virus, and some will also get a small dose of radiation to help …
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New drug cocktail targets Hard-to-Treat brain tumors
Disease control Recruiting nowThis early-stage trial is testing a drug called ASTX727 in adults with a type of brain tumor (glioma) that has an IDH mutation and has come back or is growing. The drug combines two substances to try to stop cancer cells from growing. The main goal is to find the highest safe dos…
Phase 1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Brain surgery gets a GPS: network maps may help remove tumors while preserving function
Disease control Recruiting nowThis study tests a new way to plan brain tumor surgery by creating detailed maps of each patient's brain networks using advanced MRI. Instead of relying only on standard anatomy, surgeons can see the white matter pathways and functional networks that could be affected. The goal i…
Sponsor: ARNAS Civico Di Cristina Benfratelli Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Sound waves open brain barrier to attack deadly childhood tumors
Disease control Recruiting nowThis early study tests whether focused ultrasound can safely open the blood-brain barrier in children with progressive diffuse midline glioma (DMG), a rare and aggressive brain tumor. Ten children aged 4–21 will receive oral etoposide chemotherapy after ultrasound treatment to al…
Phase 1 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Personalized drug test aims to outsmart refractory brain tumors
Knowledge-focused Recruiting nowThis study tests a lab technique called pharmacoscopy that analyzes a patient's tumor tissue to find which drugs might work best for them. It includes 40 adults with various aggressive or rare brain tumors that have not responded to standard treatments. The main goal is to see if…
Phase 2 • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Sep 21, 2026 21:00 UTC
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Massive brain tumor database aims to unlock better treatments
Knowledge-focused Recruiting nowThis study is creating a large database of brain tumor patients (70,000 people) to help doctors better understand, diagnose, and treat these cancers. It collects medical images, lab results, and patient outcomes over time. The goal is to improve prediction of tumor behavior and g…
Sponsor: Yaou Liu • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Brain tumor tissue bank aims to unlock future cures
Knowledge-focused Recruiting nowThis study collects brain tumor tissue samples from 4,000 children and adults undergoing brain surgery. The samples are stored in a tissue bank at the University of Florida for future research. The goal is to help scientists find better treatments and cures for brain tumors.
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC