Nerve sheath neoplasm
MONDO:0002547A benign or malignant neoplasm arising from the perineural cells in the sheaths surrounding the nerves. Representative examples include neurofibroma, schwannoma, and malignant peripheral nerve sheath tumor.
Also known as: neoplasm of nerve sheath, neoplasm of the nerve sheath, nerve sheath neoplasm, nerve sheath tumor, tumor of nerve sheath, tumour of nerve sheath
1562 clinical trials for this condition and its sub-types, 8 tagged with Nerve sheath neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Nerve sheath neoplasm
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Neurofibroma 17 trials · 69 incl. sub-types
11 sub-types
- Neurofibrosarcoma 33 trials
- Plexiform neurofibroma 29 trials
- Atypical neurofibroma 4 trials
- Pacinian tumor 0 trials
- Cellular neurofibroma 0 trials
- Epithelioid neurofibroma 0 trials
- Mediastinum neurofibroma 0 trials
- Neurofibroma of gallbladder 0 trials
- Neurofibroma of spinal cord 0 trials
- Neurofibroma of the esophagus 0 trials
- Neurofibroma of the heart 0 trials
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Schwannoma 9 trials · 42 incl. sub-types
10 sub-types
- Acoustic neuroma 35 trials
- Schwannomatosis 3 trials Sub-types →
- Cellular schwannoma 0 trials
- Melanotic neurilemmoma 0 trials Sub-types →
- Microcystic/reticular schwannoma 0 trials
- Peripheral nerve schwannoma 0 trials Sub-types →
- Plexiform schwannoma 0 trials
- Schwannoma of twelfth cranial nerve 0 trials
- Sympathetic neurilemmoma 0 trials
- Trigeminal schwannoma 0 trials
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Malignant peripheral nerve sheath tumor 36 trials · 38 incl. sub-types
7 sub-types
- Epithelioid malignant peripheral nerve sheath tumor 2 trials
- Childhood malignant schwannoma 1 trial
- Malignant melanocytic neoplasm of the peripheral nerve sheath 1 trial Sub-types →
- Malignant triton tumor 1 trial
- Adult malignant schwannoma 0 trials
- Malignant cardiac peripheral nerve sheath neoplasm 0 trials
- Malignant glandular tumor of peripheral nerve sheath 0 trials
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Granular cell tumor 2 trials · 3 incl. sub-types
9 sub-types
- Granular cell cancer 1 trial · 2 incl. sub-types Sub-types →
- Cutaneous granular cell tumor 0 trials · 1 incl. sub-types Sub-types →
- Benign granular cell tumor 0 trials Sub-types →
- Breast granular cell tumor 0 trials
- Congenital epulis 0 trials
- Esophageal granular cell tumor 0 trials
- Mediastinal granular cell myoblastoma 0 trials
- Neurohypophysis granular cell tumor 0 trials
- Vulvar granular cell tumor 0 trials
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Perineurioma 0 trials · 1 incl. sub-types
3 sub-types
- Malignant perineurioma 1 trial
- Extraneural perineurioma 0 trials Sub-types →
- Intraneural perineurioma 0 trials
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Neurothekeoma 0 trials
Most studied deeper sub-types
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Immunotherapy duo tackles rare nerve cancer in early trial
Disease control CompletedThis early-phase trial tested whether giving two immunotherapy drugs (nivolumab and ipilimumab) before standard surgery, chemotherapy, or radiation is safe and feasible for people with Neurofibromatosis Type 1 who have a rare malignant peripheral nerve sheath tumor. Only 13 parti…
Phase 1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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New combo therapy shows promise for rare sarcomas
Disease control CompletedThis study looked at adding the drug pazopanib to standard radiation or chemoradiation before surgery for patients with certain soft tissue sarcomas. The goal was to see if the combination is safe and helps shrink tumors more effectively. About 140 adults and children with newly …
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC