Neoplasm of esophagus

This study tests whether a special immune-boosting diet given before surgery can lower the risk of complications like infections and digestive issues in people with esophageal cancer. About 244 participants who have had chemotherapy and radiation will receive either the special d…

This study tests a new device called the Luso-Cor esophageal stent for closing leaks (fistulas) that can happen after weight-loss or cancer surgery on the stomach or esophagus. About 180 adults will be enrolled and their outcomes compared to those treated with standard stents or …

This early-phase study tests whether combining the immunotherapy drug camrelizumab with standard radiation before surgery can help shrink tumors in people with esophageal cancer. About 25 patients will receive the combination, then undergo surgery 4-8 weeks later. Researchers wil…

This trial tests whether a new AI-driven biomarker, called the Microbial-Sensory Coupling (MSC) index, can predict how well patients with esophageal squamous cell carcinoma respond to anti-PD-1 immunotherapy. The biomarker measures the spatial relationship between a specific bact…

This study aims to find early DNA changes in blood and esophageal tissue that could signal a higher risk of developing esophageal cancer. Researchers are studying 600 people with gastroesophageal reflux, Barrett's esophagus, or esophageal cancer who are already scheduled for an u…

This study follows people who have received photodynamic therapy (PDT) for various cancers, including head and neck, lung, and skin tumors. PDT uses a light-sensitive drug and a special light to destroy cancer cells while sparing healthy tissue. Researchers will review medical re…