Neonatal respiratory failure

This trial tests whether using a colorimetric carbon dioxide (CO₂) detector to guide non-invasive breathing support (ventilation) improves care for premature infants born before 32 weeks. The detector changes color to show how well the baby is exhaling CO₂, which may help doctors…

This study tests whether using lung ultrasound to guide breathing treatments can help infants with respiratory failure leave the NICU sooner. About 64 newborns will be randomly assigned to either ultrasound-guided care or standard care. The goal is to see if this approach reduces…

This study tests dexmedetomidine, a sedative that doesn't slow breathing, in 246 premature babies on ventilators. The goal is to see if it reduces the need for opioids, shortens time on the breathing machine, and improves long-term brain development. Babies will receive the drug …

This study compares a new device called ADINA to standard high-flow nasal cannula for giving oxygen to premature babies with breathing distress. About 40 babies in the NICU will take part. The goal is to see if ADINA works as well as the usual method and to check for safety issue…

This study compares two scoring systems—the Silverman-Andersen score and the Downes score—to see which better predicts when a newborn with breathing problems will need a breathing tube. Researchers will follow 220 preterm and term infants receiving noninvasive breathing support. …