Neonatal abstinence syndrome
MONDO:0005566A constellation of neurobehavioral features observed in a neonate following antenatal exposure to drugs including opioids, benzodiazepines, and selective serotonin reuptake inhibitors.
Also known as: NAS, neonatal narcotic withdrawal syndrome, neonatal withdrawal
117 clinical trials for this condition and its sub-types, 18 tagged with Neonatal abstinence syndrome itself.
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Could a simple formula change help babies born dependent on opioids gain weight better?
Disease control CompletedThis study tests whether newborns with neonatal abstinence syndrome (NAS) who receive a high-calorie formula for two weeks gain weight better than those on standard formula. The babies are managed using the Eat, Sleep, Console approach. The main goal is to see how much weight the…
Sponsor: Yale University • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New hope for pregnant women battling opioid addiction: monthly shot vs daily pill
Disease control CompletedThis study tested whether a once-monthly injection of buprenorphine works as well as daily pills to treat opioid use disorder in 140 pregnant women. The goal was to see if the monthly shot could reduce illicit opioid use during pregnancy and after birth. Results help doctors choo…
Phase 3 • Sponsor: T. John Winhusen, PhD • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Night help for moms in recovery: can respite care improve sleep and Well-Being?
Symptom relief CompletedThis study tested whether providing overnight infant care and parenting support helps new mothers with substance use disorder living in residential treatment programs. 41 mothers participated, and researchers measured how many enrolled, completed the program, and gave feedback. T…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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New study tests smarter dosing for newborns hooked on opioids
Symptom relief CompletedThis study looked at 626 full-term babies with neonatal opioid withdrawal syndrome (NOWS). Doctors compared two ways of giving medicine: one where babies get medicine at set times, and another where they only get medicine when they show withdrawal signs. The goal was to see which…
Phase 3 • Sponsor: HELP for NOWS Consortium • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New study looks inside the womb to see how opioid medications impact unborn babies
Knowledge-focused CompletedThis study looked at pregnant women being treated for opioid use disorder with two different forms of buprenorphine: a monthly shot and a daily tablet. Researchers measured drug levels in the mother's blood and checked the baby's heart rate to see how each treatment affected both…
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Opioid treatment in pregnancy: which form is safer for Baby's brain?
Knowledge-focused CompletedThis study looked at 71 babies born to mothers who took either a monthly injection or a daily tablet of buprenorphine for opioid use disorder during pregnancy. Researchers measured the babies' thinking, language, and motor skills using a standard child development test. The goal …
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC