Neonatal abstinence syndrome

This study aims to create a way for mothers with opioid use disorder to receive treatment (buprenorphine) while visiting their babies in the neonatal intensive care unit (NICU). Researchers will interview mothers and healthcare providers to understand barriers and then develop a …

This study tests a 'rooming-in' approach where mothers and babies stay together in a quiet hospital room instead of separating the baby to the NICU. About 240 full-term infants exposed to opioids during pregnancy will take part across Alberta hospitals. The goal is to reduce NICU…

This study will test a new, non-invasive device that measures blood flow and oxygen levels in the brains of newborn babies. Researchers will compare babies who were exposed to opioids before birth with those who were not. The goal is to see if the device can detect signs of opioi…

This study tests whether music therapy can help newborns who are withdrawing from opioids they were exposed to before birth. Researchers will try six different music-based approaches, including parent-sung lullabies and rhythmic sounds, to see if they calm the babies and improve …

This study looks at medical records of about 800 full-term newborns with Neonatal Opioid Withdrawal Syndrome (NOWS) to compare two standard treatments: buprenorphine and morphine. Researchers want to find out which medicine helps babies recover and become ready for discharge soon…

This study looks at tiny molecules called microRNAs in the saliva of newborns exposed to opioids before birth. Researchers want to see if these molecules can predict how severe withdrawal symptoms will be and guide treatment. The goal is to move away from one-size-fits-all care a…