Myofibroma
MONDO:0006312A benign, localized, nodular and well-circumscribed neoplasm usually seen as a congenital neoplasm or in the first year of life. It is characterized by a biphasic growth pattern and is composed of small, undifferentiated mesenchymal cells associated with branching thin-walled vessels and more mature neoplastic spindle cells with abundant eosinophilic cytoplasm in a collagenous stroma.
Also known as: myofibroma, myofibroma (morphologic abnormality), infantile hemangiopericytoma
1453 clinical trials for this condition and its sub-types, 17 tagged with Myofibroma itself.
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Old drug, new hope: mercaptopurine tested against rare cancer syndrome
Disease control Not yet recruitingThis trial tests the drug mercaptopurine in people with hereditary leiomyomatosis and renal cell carcinoma (HLRCC), a rare genetic condition that raises the risk of skin, uterine, and kidney tumors. The study aims to find the safest dose and see if the drug can shrink kidney canc…
Phase 1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can a single injection curb blood loss in fibroid surgery?
Disease control Not yet recruitingThis trial tests whether injecting a diluted solution of terlipressin, a drug that narrows blood vessels, under the outer layer of a uterine fibroid before removal can reduce blood loss during myomectomy surgery. Women scheduled for myomectomy will be randomly assigned to receive…
Sponsor: Sevil Cankaya • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Gel may shield womb from post-surgery scars, boost baby chances
Disease control Not yet recruitingThis study tests whether a gel placed inside the uterus after robotic fibroid removal can reduce scarring (adhesions) that may harm fertility. About 62 women having fibroid surgery will be randomly assigned to receive the gel or standard care. Researchers will check for adhesions…
Sponsor: Federico II University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can big data improve safety in gynecologic surgery?
Knowledge-focused Not yet recruitingThis study is a large registry that will collect detailed information from thousands of women undergoing surgery for non-cancerous gynecologic conditions like fibroids, endometriosis, and ovarian cysts. The goal is to track surgical techniques, complications, and recovery in real…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC