Multifocal motor neuropathy
MONDO:0018979Multifocal motor neuropathy (MMN) is a rare acquired immune-mediatedneuropathy characterized clinically by a purely motor deficit with conduction block and asymmetric multifocal weakness, fasciculations, and cramping.
Also known as: MMN, MMNCB, multifocal motor neuropathy with conduction block
14 clinical trials for this condition and its sub-types, 9 tagged with Multifocal motor neuropathy itself.
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New immune globulin drug shows promise for rare nerve diseases in japan
Disease control CompletedThis completed Phase 3 study tested TAK-771, a combination of immune globulin and hyaluronidase, in 26 Japanese adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) or multifocal motor neuropathy (MMN). The main goals were to check for side effects and see…
Phase 3 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New antibody drug could reduce infusions for nerve disorder
Disease control CompletedThis phase 2 trial tests an experimental drug called ARGX-117 in 54 adults with multifocal motor neuropathy (MMN), a condition that causes muscle weakness. Participants receive either ARGX-117 or a placebo by IV, and researchers check if the drug can safely delay the need for sta…
Phase 2 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Blood test may Fine-Tune IVIg dosing for rare nerve disorders
Knowledge-focused CompletedThis study looked at 20 adults with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) or multifocal motor neuropathy (MMN) who were starting intravenous immunoglobulin (IVIg) treatment. Researchers measured changes in IgG levels in the blood after the first dose to…
Sponsor: Walton Centre NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC