Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome

Human MALT1 wild-type allele is located in the vicinity of 18q21 and is approximately 79 kb in length. This allele, which encodes mucosa associated lymphoid tissue lymphoma translocation gene 1 protein, plays a role in the modulation of the nuclear factor kappa B complex signaling cascade. The gene is involved in a chromosomal translocation t(11;18)(q21;q21) with the BIRC2 gene in mucosa-associated lymphoid tissue lymphomas.

Also known as: DKFZp434L132, MALT1 wt allele, MLT, MLT1, cutaneovisceral angiomatosis-thrombocytopenia syndrome, mucosa associated lymphoid tissue lymphoma translocation Gene 1 wt allele, multifocal lymphangioendotheliomatosis with thrombocytopenia

1439 clinical trials for this condition and its sub-types, 1 tagged with Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome itself.