Monoclonal gammopathy
MONDO:0004960A condition characterized by the abnormal presence of monoclonal immunoglobulins in the blood or urine.
68 clinical trials for this condition and its sub-types, 24 tagged with Monoclonal gammopathy itself.
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Sub-types of Monoclonal gammopathy
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Monoclonal paraproteinemia disease 2 trials
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Gut bacteria drug shows promise against blood disorder
Disease control CompletedThis early-phase study tested whether the oral antibiotic rifaximin can reduce abnormal proteins in people with monoclonal gammopathy, a condition that can lead to blood cancers. Fifty adults with different types of gammopathy took the drug to see if it lowered their immunoglobul…
Phase 1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Needle vs. IV: which isatuximab method works best for myeloma?
Disease control CompletedThis study tested whether a shot under the skin (subcutaneous) works as well as an IV drip for the drug isatuximab in people with newly diagnosed multiple myeloma who are eligible for a stem cell transplant. All participants also received standard chemotherapy. The goal was to se…
Phase 3 • Sponsor: University of Heidelberg Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New drug shows promise for Hard-to-Treat blood cancer
Disease control CompletedThis study tested a drug called elranatamab in 39 Chinese patients with multiple myeloma that had stopped responding to at least three prior treatments. The drug works by helping the immune system attack cancer cells. The goal was to see if it could shrink tumors and control the …
Phase 2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC