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Mixed phenotype acute leukemia with MLL rearranged

MONDO:0850450

An acute biphenotypic leukemia that is characterized by blasts which carry a translocation between the MLL (KMT2A) gene at 11q23.3 and another gene partner.

3153 clinical trials for this condition and its sub-types, 2 tagged with Mixed phenotype acute leukemia with MLL rearranged itself.

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Where it sits in the disease tree

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Part of

↑ Acute biphenotypic leukemia (91)

Including sub-types (3153) Tagged with Mixed phenotype acute leukemia with MLL rearranged (2)

Not yet recruiting 1 Not yet finished but already full! 1

Promising new combo targets Hard-to-Treat infant leukemia

Disease control Ongoing

This study tests a new oral drug (revumenib) combined with standard chemotherapy for infants and young children with a specific type of leukemia (KMT2A-rearranged) that has returned or not responded to treatment. The goal is to see if the combination is safe and works better than…

Phase 2 • Sponsor: Children's Oncology Group • Aim: Disease control

Last updated Aug 27, 2026 00:00 UTC