Mixed phenotype acute leukemia
MONDO:0020743An acute leukemia of ambiguous lineage. It is characterized by the presence of either separate populations of blasts of more than one lineage, or one population of blasts co-expressing markers of more than one lineage.
Also known as: MPAL, mixed phenotype acute leukemia
3212 clinical trials for this condition and its sub-types, 79 tagged with Mixed phenotype acute leukemia itself.
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Browse by category →Sub-types of Mixed phenotype acute leukemia
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Acute biphenotypic leukemia 88 trials · 91 incl. sub-types
4 sub-types
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Promising combo for tough leukemias hits snag: trial ends early
Disease control Stopped earlyThis phase II trial tested a combination of two drugs, venetoclax and decitabine, in 235 patients with certain blood cancers like acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) that had come back or not responded to treatment, as well as in older patien…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug combo for kids with resistant leukemia shows early promise but study halted
Disease control Stopped earlyThis study tested a targeted cancer drug called ponatinib combined with standard chemotherapy in children and young adults up to age 21 with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) that had come back or stopped responding to other treatments. The g…
Phase 1/2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC