Please sign in to follow a disease.
Mitral valve prolapse
MONDO:0004910A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse into the left atrium, often causing mitral regurgitation. It is often a symptomless condition but may be marked by varied symptoms (e.g. chest pain, fatigue, dizziness, dyspnea, or palpitations) leading in some cases to endocarditis or ventricular tachycardia.
Also known as: barlow's syndrome, floppy mitral valve, mitral valve prolapse, mitral valve prolapse (disease), mitral valve prolapse syndrome, prolapse, mitral valve, valve, prolapse Of mitral, mitral valve prolapse, myxomatous
54 clinical trials for this condition and its sub-types, 11 tagged with Mitral valve prolapse itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Mitral valve prolapse
-
Familial mitral valve prolapse 0 trials · 1 incl. sub-types
3 sub-types
- MVP1 1 trial
- Mitral valve prolapse, myxomatous 2 0 trials
- Mitral valve prolapse, myxomatous 3 0 trials
-
Heart valve repair showdown: which surgery works best?
Disease control OngoingThis study compares two surgical techniques to fix a leaky mitral valve caused by degenerative disease. One method replaces the tiny chords that support the valve, while the other moves existing chords to a better position. The trial will follow 64 adults for one year after surge…
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
-
Can imaging and monitoring unlock the hidden dangers of mitral valve prolapse?
Knowledge-focused OngoingThis study enrolls adults aged 60 and older who are already participating in a larger trial comparing two ways to repair a leaky mitral valve. Researchers will use heart MRI scans, wearable heart monitors, and tissue samples to look for scarring in the heart muscle and abnormal h…
Sponsor: Annetine Gelijns • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
-
Can MRI predict dangerous heart rhythms in mitral valve prolapse?
Knowledge-focused OngoingThis study follows 280 people with mitral valve prolapse over 3 years to see if heart MRI scans and blood tests can predict who will develop dangerous heart rhythms or heart muscle changes. Participants undergo MRI, blood draws, and heart monitoring. The goal is to find early war…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
-
Heart MRI may outshine ultrasound for valve surgery timing
Knowledge-focused OngoingThis study looks at whether using a cardiac MRI (CMR) instead of the usual ultrasound helps doctors make better decisions about heart valve surgery for people with severe mitral regurgitation (a leaky heart valve). About 260 adults with no symptoms but severe leakage will be foll…
Sponsor: Centro Cardiologico Monzino • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC