Mitral valve prolapse
MONDO:0004910A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse into the left atrium, often causing mitral regurgitation. It is often a symptomless condition but may be marked by varied symptoms (e.g. chest pain, fatigue, dizziness, dyspnea, or palpitations) leading in some cases to endocarditis or ventricular tachycardia.
Also known as: barlow's syndrome, floppy mitral valve, mitral valve prolapse, mitral valve prolapse (disease), mitral valve prolapse syndrome, prolapse, mitral valve, valve, prolapse Of mitral, mitral valve prolapse, myxomatous
55 clinical trials for this condition and its sub-types, 12 tagged with Mitral valve prolapse itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Mitral valve prolapse
-
Familial mitral valve prolapse 0 trials · 1 incl. sub-types
3 sub-types
- MVP1 1 trial
- Mitral valve prolapse, myxomatous 2 0 trials
- Mitral valve prolapse, myxomatous 3 0 trials
-
Should asymptomatic heart valve patients get surgery now? major trial aims to settle debate
Disease control Recruiting nowThis study compares two approaches for people with a severe leaky heart valve (mitral regurgitation) who have no symptoms yet. Half will get early valve repair surgery, while the other half will be monitored closely every 6 months. The goal is to see which strategy leads to fewer…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
-
Can a new risk score predict deadly heart rhythms in mitral valve prolapse?
Diagnosis Recruiting nowMitral valve prolapse is common and usually harmless, but a small group of patients develop dangerous heart rhythms that can cause sudden cardiac arrest. Researchers at Oslo University Hospital are building and testing a risk prediction model that combines clinical exams, electro…
Sponsor: Oslo University Hospital • Aim: Diagnosis
Last updated Sep 21, 2026 14:00 UTC
-
New study aims to predict dangerous heart scarring in common valve condition
Knowledge-focused Recruiting nowThis study looks at 300 people with mitral valve prolapse, a common heart valve condition, to find ways to predict if they have scarring in the heart muscle. Researchers will use heart scans, EKGs, and other tests to build a scoring system. The goal is to better identify who is a…
Sponsor: Centro Cardiologico Monzino • Aim: Knowledge-focused
Last updated Sep 21, 2026 14:00 UTC
-
AI reads heart scans to help surgeons fix leaky valves
Knowledge-focused Recruiting nowThis study is developing an artificial intelligence (AI) system to automatically analyze 3D ultrasound images of the heart in people with mitral valve prolapse, a condition where a heart valve doesn't close properly. The AI will measure the valve's shape and movement, and create …
Sponsor: IRCCS Policlinico S. Donato • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
-
Can mitral valve surgery fix dangerous heart rhythms? new study aims to find out
Knowledge-focused Recruiting nowThis study will follow 90 people with mitral valve prolapse who are already scheduled for mitral valve surgery. Researchers will use heart scans and 7-day rhythm monitors before and 6 months after surgery to see if the procedure reduces dangerous heart rhythms and scarring. The g…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:18 UTC