Please sign in to follow a disease.

Mitchell syndrome

MONDO:0030073

A peroxisomal disease characterized by progressive episodic demyelination, sensorimotor polyneuropathy, and hearing loss that has material basis in heterozygous mutation in the ACOX1 gene on chromosome 17q25.1.

Also known as: ACOX1 upregulation, MITCH, Mitchell syndrome

2 clinical trials for this condition and its sub-types, 1 tagged with Mitchell syndrome itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Disorder of defective peroxisome oxidative status (1)

Including sub-types (2) Tagged with Mitchell syndrome (1)

Trials to join now! 1

New cream targets itch in eczema patients

Symptom relief Recruiting now

This study tests a cream called roflumilast 0.15% for itching in people with mild to moderate atopic dermatitis (eczema). About 40 participants aged 12 and older will apply the cream once daily for 4 weeks. Researchers will track how patients describe their itch and other skin se…

Phase 4 • Sponsor: Integrative Skin Science and Research • Aim: Symptom relief

Last updated Aug 15, 2026 00:00 UTC

Mitchell syndrome

Where it sits in the disease tree

New cream targets itch in eczema patients