Meningeal melanocytoma

MONDO:0016746

A usually well differentiated melanocytic neoplasm arising from the meninges. It is characterized by the presence of epithelioid, fusiform, polyhedral, and spindle melanocytes without evidence of hemorrhage, necrosis, or high mitotic activity. Presenting symptoms include headache, vomiting, and neurological manifestations. Complete excision is usually curative.

Also known as: leptomeningeal melanocytoma, melanocytoma of meninges, melanocytoma of the meninges, meninges melanocytoma

2777 clinical trials for this condition and its sub-types, 1 tagged with Meningeal melanocytoma itself.

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↑ Central nervous system melanocytic neoplasm (4)

Including sub-types (2777) Tagged with Meningeal melanocytoma (1)

Not yet finished but already full! 1

New hope for brain lining cancer: immunotherapy injected directly into spinal fluid

Disease control Ongoing

This early-phase trial is testing whether the immunotherapy drug nivolumab can help people with melanoma or lung cancer that has spread to the leptomeninges (the lining of the brain and spinal cord). The drug is given both through a vein and directly into the spinal fluid via a l…

Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Aug 21, 2026 00:00 UTC

Meningeal melanocytoma

Where it sits in the disease tree

New hope for brain lining cancer: immunotherapy injected directly into spinal fluid