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Medulloepithelioma
MONDO:0003144A rare, usually aggressive malignant embryonal neoplasm of the central nervous system occurring in children. It is characterized by the presence of neuroepithelial cells which form papillary, trabecular, or tubular structures and absence of C19MC amplification. Symptoms include headache, nausea, and vomiting.
Also known as: central nervous system medulloepithelioma, medulloepithelioma NOS (morphologic abnormality), medulloepithelioma of the central nervous system, medulloepithelioma, central nervous system, MDEP
2780 clinical trials for this condition and its sub-types, 3 tagged with Medulloepithelioma itself.
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New hope for toddlers with aggressive brain cancer: experimental spinal-fluid chemo
Disease control Recruiting nowThis early-phase study tests whether adding chemotherapy directly into the spinal fluid (intrathecal topotecan) followed by maintenance pills is feasible for children under 6 with high-risk embryonal brain tumors. About 15 children will receive this treatment after standard high-…
Early phase 1 • Sponsor: C17 Council • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Experimental drug DFMO offered to kids with rare cancers
Disease control Expanded accessThis expanded access program provides the drug DFMO to children and young adults up to age 30 with rare relapsed tumors such as neuroblastoma or medulloblastoma. The goal is to control the disease by targeting specific genetic markers. Participants take DFMO by mouth twice daily,…
Sponsor: Giselle Sholler • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC