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Medulloblastoma SHH activated

MONDO:0850197

A medulloblastoma that is characterized as a molecular subtype by activation of the sonic hedgehog (SHH) pathway and TP53 mutations that may be present or absent.

1503 clinical trials for this condition and its sub-types, 3 tagged with Medulloblastoma SHH activated itself.

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Where it sits in the disease tree

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↑ Medulloblastoma (110)

Sub-types of Medulloblastoma SHH activated

Medulloblastoma SHH activated and TP53 mutant 1 trial
Medulloblastoma SHH activated and TP53 wild-type 1 trial

Including sub-types (1503) Tagged with Medulloblastoma SHH activated (3)

Trials to join now! 1 Not yet recruiting 1 Terminated 1

Brain tumor biobank aims to unlock secrets of rare genetic mutation

Knowledge-focused Recruiting now

This study is building a biobank of blood, tissue, and health information from 300 children and adults with relapsed or hard-to-treat sonic hedgehog medulloblastoma, a type of brain tumor. Researchers want to learn more about a specific genetic mutation called U1, which may affec…

Sponsor: Mohammad H. Abu Arja • Aim: Knowledge-focused

Last updated Sep 03, 2026 00:00 UTC