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Medulloblastoma non-WNT/non-SHH

MONDO:0850198

A medulloblastoma that is characterized as a molecular subtype that is not associated with activation of the WNT pathway or sonic hedgehog (SHH) pathway and TP53 mutations are absent.

1510 clinical trials for this condition and its sub-types, 1 tagged with Medulloblastoma non-WNT/non-SHH itself.

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Where it sits in the disease tree

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Part of

↑ Medulloblastoma (111)

Sub-types of Medulloblastoma non-WNT/non-SHH

Medulloblastoma non-WNT/non-SHH group 3 3 trials
Medulloblastoma non-WNT/non-SHH group 4 2 trials

Including sub-types (1510) Tagged with Medulloblastoma non-WNT/non-SHH (1)

Trials to join now! 1

Heart drug repurposed to fight rare brain cancer in kids

Disease control Recruiting now

This study tests whether digoxin, a heart medication, can help children and young adults with a specific type of relapsed brain cancer called non-WNT/non-SHH medulloblastoma. About 23 participants aged 1 to 29 will receive digoxin to see if it stops the cancer from growing for at…

Phase 2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control

Last updated Aug 28, 2026 00:00 UTC