Mediastinal malignant germ cell tumor

MONDO:0006298

An extragonadal malignant germ cell tumor that arises from the mediastinum. This category includes seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, mixed germ cell tumors, and immature malignant teratoma.

Also known as: malignant mediastinal germ cell tumor, malignant mediastinal germ cell tumour, mediastinal germ cell tumor, malignant, mediastinal malignant germ cell tumor, thymic malignant germ cell tumor, thymic malignant germ cell tumour, malignant germ cell neoplasm of mediastinum, malignant germ cell neoplasm of the mediastinum

2765 clinical trials for this condition and its sub-types, 1 tagged with Mediastinal malignant germ cell tumor itself.

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Where it sits in the disease tree

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Part of

↑ Mediastinal cancer (191) ↑ Extragonadal germ cell cancer (22) ↑ Mediastinal germ cell tumor (2)

Sub-types of Mediastinal malignant germ cell tumor

Malignant teratoma of mediastinum 0 trials
Mediastinal yolk sac tumor 0 trials
Mediastinum seminoma 0 trials

Including sub-types (2765) Tagged with Mediastinal malignant germ cell tumor (1)

Not yet finished but already full! 1

New hope for incurable germ cell tumors? cabozantinib trial underway

Disease control Ongoing

This phase II trial is testing the drug cabozantinib in 50 patients with germ cell tumors that have not responded to standard chemotherapy. The goal is to see if the drug can stop or slow tumor growth. Patients take cabozantinib daily until the disease worsens or side effects bec…

Phase 2 • Sponsor: Jennifer King • Aim: Disease control

Last updated Jun 27, 2026 08:11 UTC

Mediastinal malignant germ cell tumor

Where it sits in the disease tree

New hope for incurable germ cell tumors? cabozantinib trial underway