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Mastocytosis

MONDO:0007950

A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ systems. It is a heterogeneous group of neoplasms, ranging from cutaneous proliferations which may regress spontaneously, to aggressive neoplasms associated with organ failure and short survival.

Also known as: Mast cell disease, mastocytosis, MAST cell disease, urticaria pigmentosa

1877 clinical trials for this condition and its sub-types, 15 tagged with Mastocytosis itself.

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Where it sits in the disease tree

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Part of

↑ Leukocyte disorder (3572) ↑ Mast cell neoplasm (34)

Sub-types of Mastocytosis

Systemic mastocytosis 11 trials · 24 incl. sub-types
5 sub-types
- Mast cell leukemia 9 trials
- Indolent systemic mastocytosis 8 trials Sub-types →
- Aggressive systemic mastocytosis 4 trials Sub-types →
- Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease 4 trials
- Extracutaneous mastocytoma 0 trials
Cutaneous mastocytosis 1 trial
3 sub-types
- Cutaneous mastocytoma 0 trials Sub-types →
- Diffuse cutaneous mastocytosis 0 trials Sub-types →
- Maculopapular cutaneous mastocytosis 0 trials Sub-types →
Acute mast cell leukemia 0 trials
Chronic mast cell leukemia 0 trials
Mast cell sarcoma 0 trials

Most studied deeper sub-types

Smouldering systemic mastocytosis (3) Isolated bone marrow mastocytosis (2) Bullous diffuse cutaneous mastocytosis (0) Cutaneous solitary mastocytoma (0) Lymphoadenopathic mastocytosis with eosinophilia (0) Nodular urticaria pigmentosa (0) Plaque-form urticaria pigmentosa (0) Pseudoxanthomatous diffuse cutaneous mastocytosis (0) Telangiectasia macularis eruptiva perstans (0) Typical urticaria pigmentosa (0)

Including sub-types (1877) Tagged with Mastocytosis (15)

Trials to join now! 10 Not yet finished but already full! 2 Completed 3

Mastocytosis

Where it sits in the disease tree

Most studied deeper sub-types

New drug aims to ease daily misery of rare mast cell disease

Rare disease pregnancy study pulled before it began