Mast cell leukemia

MONDO:0020334

Mast cell leukemia is a malignant form of systemic mastocytosis (SM) characterized, most of the time, by the presence of circulating mast cells.

Also known as: Mast cell leukaemia, Mast cell leukemia, aleukemic mast cell leukaemia, aleukemic mast cell leukemia, mast-cell leukaemia, mast-cell leukemia, SMMCL

1866 clinical trials for this condition and its sub-types, 9 tagged with Mast cell leukemia itself.

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Where it sits in the disease tree

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Part of

↑ Leukemia (2561) ↑ Systemic mastocytosis (24)

Including sub-types (1866) Tagged with Mast cell leukemia (9)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 3 Completed 1

New targeted pill shows promise for rare blood cancer

Disease control Completed

This Phase 2 study tested avapritinib, a daily tablet that targets a specific genetic mutation, in 107 people with advanced systemic mastocytosis (a rare blood cancer). The main goal was to see how many patients had their tumors shrink or symptoms improve. Results suggest the dru…

Phase 2 • Sponsor: Blueprint Medicines Corporation • Aim: Disease control

Last updated Jun 27, 2026 12:24 UTC

Mast cell leukemia

Where it sits in the disease tree

New targeted pill shows promise for rare blood cancer