Malignant giant cell tumor of soft parts
MONDO:0003561An undifferentiated pleomorphic sarcoma characterized by the presence of osteoclast-like giant cells and cellular pleomorphism.
Also known as: giant cell fibrous histiocytoma, giant cell malignant fibrous histiocytoma, malignant Osteoclastoma, malignant giant cell neoplasm of soft parts, malignant giant cell tumor of soft parts, malignant giant cell tumor of soft parts (morphologic abnormality), malignant giant cell tumour of soft parts (morphologic abnormality), undifferentiated pleomorphic sarcoma with osteoclast-like giant cells
2835 clinical trials for this condition and its sub-types, 3 tagged with Malignant giant cell tumor of soft parts itself.
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New hope for rare sarcomas: chemo plus immunotherapy combo enters phase III trial
Disease control Recruiting nowThis Phase III trial tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (doxorubicin) helps people with advanced dedifferentiated liposarcoma or undifferentiated pleomorphic sarcoma live longer without their cancer worsening. About 365 adults whose…
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New hope for rare childhood cancer: drug cocktail aims to shrink tumors and prevent return
Disease control Recruiting nowThis study is for children and young adults (up to age 30) with a rare type of soft tissue cancer called non-rhabdomyosarcoma. It tests whether adding the drugs pazopanib and selinexor to standard chemotherapy can improve outcomes. Participants receive treatment tailored to their…
Phase 1/2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC