Malignant germ cell tumor
MONDO:0006290A gonadal or extragonadal malignant neoplasm that arises from germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, and seminoma.
Also known as: cancer of germ cell, germ cell cancer, germ cell tumor, malignant, malignant germ cell neoplasm, malignant germ cell tumor, malignant neoplasm of germ cell, malignant neoplasm of the germ cell, malignant tumor of germ cell
2792 clinical trials for this condition and its sub-types, 14 tagged with Malignant germ cell tumor itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Malignant germ cell tumor
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Malignant testicular germ cell tumor 14 trials · 36 incl. sub-types
6 sub-types
- Testis refractory cancer 13 trials
- Testicular seminoma 8 trials Sub-types →
- Testicular non-seminomatous germ cell cancer 3 trials · 4 incl. sub-types Sub-types →
- Mixed testicular germ cell cancer 2 trials Sub-types →
- Malignant teratoma of testis 0 trials
- Testis polyembryoma 0 trials
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Seminoma 22 trials
2 sub-types
- Testicular seminoma 8 trials Sub-types →
- Extragonadal seminoma 1 trial Sub-types →
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Extragonadal germ cell cancer 0 trials · 22 incl. sub-types
9 sub-types
- Extragonadal nonseminomatous germ cell tumor 5 trials · 19 incl. sub-types Sub-types →
- Extragonadal germinoma 0 trials · 4 incl. sub-types Sub-types →
- Malignant pineal area germ cell neoplasm 2 trials · 3 incl. sub-types Sub-types →
- Extragonadal seminoma 1 trial Sub-types →
- Mediastinal malignant germ cell tumor 1 trial Sub-types →
- Malignant cardiac germ cell tumor 0 trials
- Malignant gastric germ cell tumor 0 trials Sub-types →
- Malignant peritoneal germ cell tumor 0 trials
- Mixed extragonadal germ cell cancer 0 trials Sub-types →
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Germinoma 7 trials · 9 incl. sub-types
1 sub-type
- Extragonadal germinoma 0 trials · 4 incl. sub-types Sub-types →
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Mixed germ cell tumor 3 trials · 5 incl. sub-types
6 sub-types
- Mixed testicular germ cell cancer 2 trials Sub-types →
- Mixed extragonadal germ cell cancer 0 trials Sub-types →
- Mixed germ cell tumor of vulva 0 trials
- Mixed teratoma and seminoma 0 trials
- Ovarian mixed germ cell neoplasm 0 trials
- Teratocarcinoma 0 trials
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Malignant germ cell tumor of ovary 2 trials · 4 incl. sub-types
4 sub-types
- Ovarian primitive germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
- Choriocarcinoma of ovary 1 trial Sub-types →
- Malignant dysgerminomatous germ cell tumor of ovary 0 trials
- Primary non-gestational choriocarcinoma of ovary 0 trials
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Malignant teratoma 1 trial · 3 incl. sub-types
7 sub-types
- Immature ovarian teratoma 1 trial · 2 incl. sub-types Sub-types →
- Pineal region immature teratoma 1 trial
- Immature extragonadal teratoma 0 trials
- Immature gastric teratoma 0 trials
- Intermediate malignant teratoma 0 trials
- Malignant teratoma of mediastinum 0 trials
- Malignant teratoma of testis 0 trials
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Malignant childhood germ cell neoplasm 0 trials · 3 incl. sub-types
12 sub-types
- Childhood central nervous system germinoma 1 trial Sub-types →
- Childhood endodermal sinus tumor 0 trials · 1 incl. sub-types Sub-types →
- Childhood immature teratoma of ovary 1 trial
- Childhood central nervous system embryonal carcinoma 0 trials
- Childhood central nervous system mixed germ cell tumor 0 trials
- Childhood choriocarcinoma of the ovary 0 trials
- Childhood embryonal testis carcinoma 0 trials
- Childhood ovarian embryonal carcinoma 0 trials
- Childhood testicular choriocarcinoma 0 trials
- Childhood testicular mixed germ cell cancer 0 trials Sub-types →
- Pediatric CNS choriocarcinoma 0 trials
- Pediatric ovarian dysgerminoma 0 trials
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Dysgerminoma 1 trial
2 sub-types
- Dysgerminoma of ovary 0 trials Sub-types →
- Pineal region dysgerminoma 0 trials
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1 sub-type
- Uterine corpus choriocarcinoma 0 trials
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Pulmonary artery choriocarcinoma 0 trials
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Vaginal germ cell malignant tumor 0 trials
1 sub-type
- Vaginal yolk sac tumor 0 trials
Most studied deeper sub-types
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New drug targets tough childhood cancers with genetic flaws
Disease control CompletedThis phase 2 trial tested the drug samotolisib in 18 children and young adults with advanced solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that had spread, returned, or stopped responding to treatment. Only patients whose tumors had specific mutations in the TSC or…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a simple spit test predict chemo-related deafness in kids?
Knowledge-focused CompletedThis study looked at 119 children who had platinum-based chemotherapy for certain cancers. Researchers wanted to find out if certain genes make some kids more likely to develop hearing loss from the treatment. By analyzing DNA from saliva samples, they hope to identify high-risk …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC