Malignant endocrine neoplasm
MONDO:0021069A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma.
Also known as: endocrine neoplasm, Endocrine tumour, cancer of endocrine gland, endocrine cancer, endocrine gland cancer, endocrine neoplasm, malignant, malignant endocrine gland neoplasm, malignant endocrine gland tumor
5472 clinical trials for this condition and its sub-types, 17 tagged with Malignant endocrine neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Malignant endocrine neoplasm
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Liver cancer 254 trials · 1,700 incl. sub-types
5 sub-types
- Carcinoma of liver and intrahepatic biliary tract 36 trials · 1,455 incl. sub-types Sub-types →
- Biliary tract cancer 240 trials · 614 incl. sub-types Sub-types →
- Liver sarcoma 1 trial · 10 incl. sub-types Sub-types →
- Liver lymphoma 1 trial Sub-types →
- Calcifying nested epithelial stromal tumor of the liver 0 trials
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Neuroendocrine carcinoma 106 trials · 744 incl. sub-types
12 sub-types
- Small cell carcinoma 26 trials · 542 incl. sub-types Sub-types →
- Cutaneous neuroendocrine carcinoma 78 trials
- Medullary thyroid gland carcinoma 42 trials · 53 incl. sub-types Sub-types →
- Large cell neuroendocrine carcinoma 12 trials · 31 incl. sub-types Sub-types →
- Pancreatic endocrine carcinoma 12 trials Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Liver neuroendocrine carcinoma 3 trials Sub-types →
- Thymic neuroendocrine carcinoma 3 trials Sub-types →
- Goblet cell carcinoma 2 trials
- Anal canal neuroendocrine neoplasm 1 trial Sub-types →
- Combined lung carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Vulvar neuroendocrine carcinoma 0 trials Sub-types →
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Thyroid cancer 166 trials · 328 incl. sub-types
3 sub-types
- Thyroid gland carcinoma 41 trials · 237 incl. sub-types Sub-types →
- Thyroid lymphoma 0 trials Sub-types →
- Thyroid sarcoma 0 trials Sub-types →
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Thymus cancer 10 trials · 225 incl. sub-types
2 sub-types
- Thymus lymphoma 0 trials · 175 incl. sub-types Sub-types →
- Thymic carcinoma 41 trials · 44 incl. sub-types Sub-types →
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Adrenal gland cancer 16 trials · 62 incl. sub-types
3 sub-types
- Adrenal carcinoma 34 trials · 52 incl. sub-types Sub-types →
- Malignant tumor of adrenal cortex 0 trials · 42 incl. sub-types Sub-types →
- Adrenal medulla cancer 0 trials · 11 incl. sub-types Sub-types →
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Pineal gland cancer 0 trials · 19 incl. sub-types
3 sub-types
- Pineoblastoma 15 trials Sub-types →
- Malignant pineal area germ cell neoplasm 2 trials · 3 incl. sub-types Sub-types →
- Pineal gland astrocytoma 1 trial
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Malignant tumor of parathyroid gland 2 trials · 6 incl. sub-types
1 sub-type
- Parathyroid gland carcinoma 4 trials
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Pituitary cancer 2 trials · 4 incl. sub-types
4 sub-types
- Pituitary adenocarcinoma 3 trials Sub-types →
- Growth hormone-producing pituitary gland carcinoma 0 trials
- Pituicytoma 0 trials
- Pituitary blastoma 0 trials
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Ovarian neuroendocrine neoplasm 0 trials · 2 incl. sub-types
2 sub-types
- Ovarian small cell carcinoma 1 trial · 2 incl. sub-types Sub-types →
- Ovarian large-cell neuroendocrine carcinoma 0 trials
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Malignant carotid body paraganglioma 0 trials
Most studied deeper sub-types
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Engineered immune cells take on metastatic tumors in new trial
Disease control Recruiting nowThis phase 2 trial tests whether a patient's own white blood cells, genetically modified in a lab to recognize and attack their specific tumor mutations, can shrink metastatic cancers. Participants include people with several advanced solid tumors or multiple myeloma who have exh…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Breathing in chemo: new hope for lung metastases?
Disease control Recruiting nowThis early-phase study tests a chemotherapy drug (gemcitabine) given as a mist to breathe in. It is for people whose solid tumors have spread to the lungs and who have no standard treatment options. The main goal is to find the safest dose and watch for side effects. Up to 44 par…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New targeted drug shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug called repotrectinib in people with advanced solid tumors that have certain gene changes (ALK, ROS1, or NTRK). The trial has two parts: first, finding a safe dose, and second, seeing how well the drug shrinks tumors. About 500 adults with advanced canc…
Phase 1/2 • Sponsor: Turning Point Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New PET tracer aims to reveal hidden inflammation in cancer patients
Diagnosis Recruiting nowThis early-stage study tests a new imaging agent called 18F-4FN for PET scans to safely detect inflammation in the body. It involves 55 adults with cancer who are on immunotherapy or have suspected inflammation. The goal is to see if this agent can highlight areas of inflammation…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Aug 22, 2026 00:00 UTC
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Scientists dive deep into endocrine tumors to unlock molecular secrets
Knowledge-focused Recruiting nowThis study enrolls people with endocrine tumors (such as thyroid, parathyroid, adrenal, or pancreatic tumors) who are scheduled for surgery or biopsy. Researchers collect samples of the tumor, nearby healthy tissue, blood, and urine to analyze genetic and molecular changes. The g…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can we predict and treat cancer wasting better? a new study investigates
Knowledge-focused Recruiting nowThis study is looking at why some people with advanced cancer lose weight and muscle, a condition called cachexia. Researchers will follow 800 patients with advanced lung, pancreatic, or colorectal cancer to see if there are distinct subtypes of cachexia based on symptoms, biomar…
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Dietary change explored as cancer support strategy
Knowledge-focused Recruiting nowThis early-stage study tests whether people with advanced solid tumors can safely follow a diet low in methionine, an amino acid found in many proteins. Researchers will measure how well participants stick to the diet, check for side effects, and track changes in blood methionine…
Early phase 1 • Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC