Malignant adrenal gland pheochromocytoma

MONDO:0006288

A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis include lymph nodes, bones, liver, and lung. Morphologic features associated with malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular invasion, tumor cell necrosis, and high mitotic activity.

Also known as: adrenal gland pheochromocytoma, malignant, malignant adrenal gland Chromaffinoma, malignant adrenal gland chromaffin neoplasm, malignant adrenal gland chromaffin paraganglioma, malignant adrenal gland chromaffin tumor, malignant adrenal gland chromaffin tumour, malignant adrenal gland paraganglioma, malignant adrenal gland pheochromocytoma

2828 clinical trials for this condition and its sub-types, 11 tagged with Malignant adrenal gland pheochromocytoma itself.

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Where it sits in the disease tree

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↑ Central nervous system cancer (1706) ↑ Neuroendocrine carcinoma (744) ↑ Peripheral nervous system cancer (67) ↑ Adrenal gland pheochromocytoma (16) ↑ Adrenal medulla carcinoma (11)

Including sub-types (2828) Tagged with Malignant adrenal gland pheochromocytoma (11)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 3 Completed 2 Terminated 1

New drug aims to shrink rare adrenal tumors

Disease control Not yet recruiting

This phase 2 trial tests an oral drug called zanzalintinib in people with metastatic pheochromocytoma or paraganglioma that cannot be surgically removed and is growing. The study measures how many participants see their tumors shrink or stop growing. All participants take the dru…

Phase 2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control

Last updated Jul 22, 2026 00:00 UTC

Malignant adrenal gland pheochromocytoma

Where it sits in the disease tree

New drug aims to shrink rare adrenal tumors