Malignant adrenal gland pheochromocytoma
MONDO:0006288A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis include lymph nodes, bones, liver, and lung. Morphologic features associated with malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular invasion, tumor cell necrosis, and high mitotic activity.
Also known as: adrenal gland pheochromocytoma, malignant, malignant adrenal gland Chromaffinoma, malignant adrenal gland chromaffin neoplasm, malignant adrenal gland chromaffin paraganglioma, malignant adrenal gland chromaffin tumor, malignant adrenal gland chromaffin tumour, malignant adrenal gland paraganglioma, malignant adrenal gland pheochromocytoma
2828 clinical trials for this condition and its sub-types, 11 tagged with Malignant adrenal gland pheochromocytoma itself.
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Radioactive therapy takes aim at resistant childhood cancer
Disease control Recruiting nowThis study tests a radioactive drug called I-MIBG in people with resistant neuroblastoma or related tumors (pheochromocytoma and paraganglioma). The drug is designed to deliver radiation directly to cancer cells. Researchers want to see if it can shrink tumors and how safe it is.…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Radioactive 'Smart Bomb' targets tough childhood cancer
Disease control Expanded accessThis expanded access program provides 131 I-MIBG therapy for children and young adults with refractory or relapsed neuroblastoma, a cancer that hasn't responded to standard treatments. The therapy uses a radioactive compound that is taken up by cancer cells, delivering radiation …
Sponsor: John Maris • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could a cancer drug quiet overactive adrenal hormones? a new study investigates.
Knowledge-focused Recruiting nowThis pilot study looks at how belzutifan, a drug already used for some tumors, changes the production of adrenaline-like hormones in people with pheochromocytoma and paraganglioma (PPGL). Over 5 days, researchers measure key substances in the hormone-making process to see if belz…
Phase 2 • Sponsor: Cambridge University Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Can molecular markers revolutionize adrenal cancer management?
Knowledge-focused Recruiting nowThis study aims to bring molecular markers into routine care for patients with rare adrenal cancers. Researchers will collect blood, urine, and tumor samples from 450 patients before and after surgery to see if these markers can guide treatment decisions. The goal is to make thes…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC