Male reproductive system disorder
MONDO:0003150A disease involving the male reproductive system.
Also known as: Male reproductive system disease, Male reproductive system disorder, disease of male reproductive system, disease or disorder of male reproductive system, disorder of Male reproductive system, disorder of male reproductive system, male reproductive disease, male reproductive system disease
2836 clinical trials for this condition and its sub-types, 11 tagged with Male reproductive system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Male reproductive system disorder
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Prostate disorder 16 trials · 2,448 incl. sub-types
5 sub-types
- Prostate neoplasm 126 trials · 2,233 incl. sub-types Sub-types →
- Benign prostatic hyperplasia 226 trials
- Prostatitis 4 trials · 15 incl. sub-types Sub-types →
- Prostate calculus 0 trials
- Prostatic cyst 0 trials
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Male reproductive system neoplasm 1 trial · 2,378 incl. sub-types
6 sub-types
- Male reproductive organ cancer 22 trials · 2,355 incl. sub-types Sub-types →
- Neoplasm of testis 4 trials · 101 incl. sub-types Sub-types →
- Penile neoplasm 30 trials · 65 incl. sub-types Sub-types →
- Scrotum neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Epididymal neoplasm 0 trials Sub-types →
- Lipoma of spermatic cord 0 trials
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Penile disorder 3 trials · 195 incl. sub-types
7 sub-types
- Erectile dysfunction 122 trials · 126 incl. sub-types Sub-types →
- Penile neoplasm 30 trials · 65 incl. sub-types Sub-types →
- Phimosis 2 trials Sub-types →
- Balanitis 0 trials · 1 incl. sub-types Sub-types →
- Leukoplakia of penis 0 trials
- Posthitis 0 trials Sub-types →
- Vascular disorder of penis 0 trials
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Testicular disorder 2 trials · 111 incl. sub-types
8 sub-types
- Neoplasm of testis 4 trials · 101 incl. sub-types Sub-types →
- Spermatic cord torsion 7 trials
- Orchitis 1 trial · 2 incl. sub-types Sub-types →
- Atrophy of testis 1 trial
- Acquired testicular failure 0 trials
- Chylocele of tunica vaginalis 0 trials
- Testicular dysgenesis syndrome 0 trials
- Testicular infarct 0 trials
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Male infertility 74 trials · 92 incl. sub-types
8 sub-types
- Azoospermia 25 trials
- Oligospermia 20 trials
- Spermatogenic failure 1 trial · 12 incl. sub-types Sub-types →
- Oligoasthenoteratozoospermia 11 trials
- Partial chromosome Y deletion 0 trials · 5 incl. sub-types Sub-types →
- Male infertility with teratozoospermia due to single gene mutation 0 trials · 1 incl. sub-types Sub-types →
- Infertility due to extratesticular cause 0 trials
- Male infertility due to acephalic spermatozoa 0 trials
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Scrotal disorder 2 trials · 19 incl. sub-types
2 sub-types
- Varicocele 15 trials
- Scrotum neoplasm 1 trial · 2 incl. sub-types Sub-types →
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Cryptorchidism 14 trials
1 sub-type
- Arroyo Garcia Cimadevilla syndrome 0 trials
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Hydrocele 6 trials
1 sub-type
- Infected hydrocele 0 trials
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Epididymitis 2 trials
2 sub-types
- Epididymo-orchitis 0 trials Sub-types →
- Tuberculous epididymitis 0 trials
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Fournier gangrene 2 trials
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3 sub-types
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Isolated micropenis 1 trial
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Spermatocele 1 trial
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6 sub-types
- Benign neoplasm of epididymis 0 trials Sub-types →
- Benign neoplasm of penis 0 trials
- Benign neoplasm of prostate 0 trials Sub-types →
- Benign neoplasm of scrotum 0 trials Sub-types →
- Benign neoplasm of testis 0 trials Sub-types →
- Lipoma of spermatic cord 0 trials
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Congenital agenesis of the scrotum 0 trials
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Congenital megaprepuce 0 trials
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Diphallia 0 trials
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Epididymis disease 0 trials
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Male genital organ stricture 0 trials
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Male genital organ vascular disease 0 trials
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Male genital tuberculosis 0 trials
1 sub-type
- Tuberculous epididymitis 0 trials
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Penoscrotal transposition 0 trials
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Posterior hypospadias 0 trials
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Postorgasmic illness syndrome 0 trials
Most studied deeper sub-types
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Can a second injection fix penile curvature?
Disease control OngoingThis study tests whether a drug called Xiaflex (collagenase clostridium histolyticum) is safe and effective for men with Peyronie's disease who have already tried platelet-rich plasma (PRP) injections. Twelve men with stable penile curvature between 30 and 90 degrees will receive…
Phase 4 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New radioactive therapy aims to control advanced prostate cancer
Disease control OngoingThis early-stage study tests a radioactive drug called 225Ac-PSMA-617 in men with PSMA-positive prostate cancer that has stopped responding to hormone therapy. The goal is to find a safe dose and see if it can help control the cancer, even in men who have already received a simil…
Phase 1 • Sponsor: Endocyte • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Can cannabis alter sperm and testosterone? a trial seeks answers
Knowledge-focused CancelledThis trial explores whether cannabis use changes male reproductive health, including sperm quality, testosterone levels, and genetic markers in sperm. Men who use cannabis regularly and those who don't will be randomly assigned to vape cannabis with different THC doses, a placebo…
Phase 1 • Sponsor: Kanako Hayashi • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC