Male breast carcinoma

This trial tests two ways of giving chemotherapy after breast cancer surgery. One group gets the drugs doxorubicin and cyclophosphamide every two weeks, while the other gets them on a continuous schedule, and both groups then receive paclitaxel either every two weeks or weekly. T…

This phase 3 trial tested whether adding the drug everolimus to standard hormone therapy helps prevent breast cancer from returning in nearly 2,000 patients with high-risk, hormone receptor-positive, HER2-negative breast cancer. Participants received either hormone therapy plus e…

This phase 2 trial tested two different chemotherapy regimens, with or without the targeted drug trastuzumab, given before surgery to patients with stage II or III breast cancer. The goal was to see which combination better eliminated cancer cells in the breast and lymph nodes. A…

This study tests two different vaccines designed to prevent HER-2 positive breast cancer from coming back in people who have already completed initial treatment. About 119 participants who had surgery after chemotherapy will receive one of the two vaccines, followed by booster sh…

This study looks at how age changes the way the body handles a breast cancer drug called nab-paclitaxel. Researchers are studying 40 people with metastatic breast cancer to see if older patients process the drug differently. The goal is to make chemotherapy safer and more effecti…

This study collects medical information and tumor samples from 200 men with breast cancer to better understand the disease. Researchers will analyze patient characteristics, treatments, and outcomes over time. The goal is to learn more about male breast cancer, which is rare and …