Lynch syndrome 5

An autosomal dominant hereditary neoplastic syndrome caused by pathogenic variants in the MSH6 mismatch repair gene. It is characterized by an increased risk of colorectal cancer in the absence of extensive polyposis, endometrial, ovarian, gastric, small intestinal, and urinary tract cancers, often occuring at younger ages.

Also known as: MSH6 hereditary nonpolyposis colon cancer, MSH6-related Lynch Syndrome, colorectal cancer, hereditary nonpolyposis, type 5, hereditary nonpolyposis colon cancer caused by mutation in MSH6, HNPCC5

2904 clinical trials for this condition and its sub-types, 0 tagged with Lynch syndrome 5 itself.