Lymphomatoid papulosis
MONDO:0020326Lymphomatoid papulosis (LyP) is a rare cutaneous condition characterized by chronic, recurrent, and self-regressing papulonodular skin eruptions. It belongs to the spectrum of primary cutaneous CD30+ lymphoproliferative disorders, along with primary cutaneous anaplastic large cell lymphoma (primary C-ALCL) with which it shares overlapping clinical and histopathologic features.
Also known as: LyP, LYP
3118 clinical trials for this condition and its sub-types, 9 tagged with Lymphomatoid papulosis itself.
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Could a lower dose of this cancer drug be just as good?
Disease control Recruiting nowThis study is testing whether a lower dose of the drug brentuximab vedotin can still effectively treat three types of skin lymphoma: mycosis fungoides, Sezary syndrome, and lymphomatoid papulosis. The goal is to see if reducing the dose can maintain benefits while possibly loweri…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New hope for rare skin cancer: experimental drug enters human trial
Disease control Recruiting nowThis early-phase trial tests an investigational drug called ropeginterferon in 38 adults with cutaneous T-cell lymphoma (CTCL), a rare type of skin cancer. Participants must have tried at least two prior treatments without success. The main goals are to find the safest dose and s…
Phase 1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Researchers track rare skin cancers in kids over decades
Knowledge-focused Recruiting nowThis study follows 100 people diagnosed before age 20 with mycosis fungoides or lymphomatoid papulosis, rare skin conditions. Researchers will check their health and ask about long-term effects. The goal is to understand how these diseases progress over time, not to test a new tr…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Scientists investigate skin microbiome in rare lymphoma
Knowledge-focused Recruiting nowThis study looks at the bacteria living on the skin of people with cutaneous T cell lymphoma, a rare type of skin cancer. Researchers will compare these bacteria to those on healthy people and people with other skin conditions like psoriasis. The goal is to understand if certain …
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Scientists launch tissue collection to unlock lymphoma mysteries
Knowledge-focused Recruiting nowThis study collects and stores tissue samples from people with cutaneous T-cell lymphoma (CTCL) and healthy volunteers. Researchers will use these samples to study how T cells change in CTCL. No treatment is given—the goal is to gather information for future research. Up to 400 p…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC