Lymphomatoid papulosis

MONDO:0020326

Lymphomatoid papulosis (LyP) is a rare cutaneous condition characterized by chronic, recurrent, and self-regressing papulonodular skin eruptions. It belongs to the spectrum of primary cutaneous CD30+ lymphoproliferative disorders, along with primary cutaneous anaplastic large cell lymphoma (primary C-ALCL) with which it shares overlapping clinical and histopathologic features.

Also known as: LyP, LYP

3118 clinical trials for this condition and its sub-types, 9 tagged with Lymphomatoid papulosis itself.

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Where it sits in the disease tree

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Part of

↑ Primary cutaneous CD30+ T-cell lymphoproliferative disease (15)

Including sub-types (3118) Tagged with Lymphomatoid papulosis (9)

Trials to join now! 5 Not yet finished but already full! 3 Completed 1

Can a drug duo outsmart resistant T-Cell lymphoma?

Disease control Completed

This phase II trial is testing whether combining brentuximab vedotin, a targeted antibody-drug conjugate, with lenalidomide, a chemotherapy drug, can shrink tumors in people with T-cell lymphoma that has relapsed or not responded to earlier treatment. The study enrolls adults wit…

Phase 2 • Sponsor: John Reneau • Aim: Disease control

Last updated Aug 15, 2026 00:00 UTC

Lymphomatoid papulosis

Where it sits in the disease tree

Can a drug duo outsmart resistant T-Cell lymphoma?